Dynamics of dendritic cell migration and the subsequent induction of protective immunity in the lung after repeated airway challenges by nontypeable Haemophilus influenzae outer membrane protein

To determine the dynamics of dendritic cell (DCs) migration and their role in recurrent infections by nontypeable Haemophilus influenzae (NTHi), the migration of mature DC into pulmonary lymph nodes (LN) and the development of a P6-specific immune response and bacterial clearance in the lung were ex...

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Veröffentlicht in:	Vaccine 2006-07, Vol.24 (31), p.5896-5903
Hauptverfasser:	Kurita, Shin-ichi, Koyama, Jun, Onizuka, Shozaburo, Motomura, Kazushi, Watanabe, Hiroshi, Watanabe, Kiwao, Senba, Masachika, Apicella, Michael A., Murphy, Timothy F., Yoneyama, Horoyuki, Matsushima, Kouji, Nagatake, Tsuyoshi, Oishi, Kazunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Applied microbiology Bacterial Outer Membrane Proteins - immunology Bacteriology Biological and medical sciences Cell Movement - immunology Cells, Cultured Dendritic cell Dendritic Cells - immunology Fundamental and applied biological sciences. Psychology Haemophilus Infections - immunology Haemophilus Infections - prevention & control Haemophilus influenzae Haemophilus influenzae - immunology Haemophilus Vaccines - immunology Humans Lung - cytology Lung - immunology Mice Microbiology Miscellaneous Nontypeable Haemophilus influenzae P6 protein Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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