Amelogenesis Imperfecta and Unusual Gingival Hyperplasia

Background: Amelogenesis imperfecta (AI) is a group of hereditary conditions that primarily involves the defective formation and/or calcification of enamel. The association of AI with gingival enlargement‐like lesions has also been reported. Methods: This paper reports a case of a hypoplastic AI associated with unusual generalized gingival hyperplasia. Results: Histological aspect of the gingival growth was characterized by a dense connective tissue with a mild mononuclear inflammatory infiltrate, calcified bodies, and islands of odontogenic epithelium. Conclusion: The present case represents a very interesting demonstration of the fact that, although rare, AI may be associated with generalized gingival enlargement. J Periodontol 2005;76:1563‐1566.