Human CD8 + cytotoxic T cell responses to adenovirus capsid proteins

Adenoviruses (Ads) cause fatal disease in allogeneic stem cell transplant recipients, but there is no established therapy. Ad-specific CD8 + T cells were detected in PBMC from healthy adults at a mean frequency of 77 per 10 5 CD8 + T cells (range 8–260) by interferon-γ ELISPOT and cytokine flow cyto...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2006-07, Vol.350 (2), p.312-322
Hauptverfasser:	Tang, Jie, Olive, Melanie, Pulmanausahakul, Rojjanaporn, Schnell, Matthias, Flomenberg, Neal, Eisenlohr, Laurence, Flomenberg, Phyllis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - immunology Adenoviridae - pathogenicity Adenovirus Adult Amino Acid Sequence Base Sequence Capsid Proteins - chemistry Capsid Proteins - immunology CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - virology CD8 T lymphocytes CTL DNA Primers Epitopes Hexon Histocompatibility Antigens Class I - immunology HLA A2 Humans Immunologic Memory Immunotherapy Molecular Sequence Data Stem cell transplantation T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - virology
Online-Zugang:	Volltext
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