Search for Genetic Factors Associated with Susceptibility to Multiple Sclerosis

: Multiple sclerosis (MS) is a cell‐mediated autoimmune disease characterized by type‐1 cytokine production. Environmental and individual genetic background might influence this response particularly in cytokine gene polymorphisms. We evaluated whether polymorphisms of interleukin (IL)‐10, IL‐12, a...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2006-05, Vol.1067 (1), p.264-269
Hauptverfasser:	FORTE, GIUSI IRMA, RAGONESE, PAOLO, SALEMI, GIUSEPPE, SCOLA, LETIZIA, CANDORE, GIUSEPPINA, D'AMELIO, MARCO, CRIVELLO, ANTONIO, DI BENEDETTO, NORMA, NUZZO, DOMENICO, GIACALONE, ANTONIO, LIO, DOMENICO, CARUSO, CALOGERO
Format:	Artikel
Sprache:	eng
Schlagworte:	Case-Control Studies cytokine polymorphisms Cytokines - genetics Disease Susceptibility Female Gene Frequency Genetic Predisposition to Disease - genetics Humans IL-10 IL-12 Interleukin-10 - genetics Interleukin-12 - genetics Male Multiple sclerosis Multiple Sclerosis - genetics Polymorphism, Genetic Polymorphism, Single Nucleotide SNP TNF-α Tumor Necrosis Factor-alpha - genetics
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