Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients
In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive oper...
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Veröffentlicht in: | The American journal of surgery 2005-10, Vol.190 (4), p.595-597 |
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container_title | The American journal of surgery |
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creator | Klauber-DeMore, Nancy Calvo, Benjamin F. Hultman, C. Scott Kim, Hong Jin Meyers, Michael O. Damitz, Lynn Frank, Jill S. Stitzenberg, Karen B. Sartor, Carolyn I. Ollila, David W. |
description | In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures.
Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.
Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.
Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction. |
doi_str_mv | 10.1016/j.amjsurg.2005.06.020 |
format | Article |
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Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.
Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.
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Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.
Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.
Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction.</description><subject>Adult</subject><subject>Aged</subject><subject>Axilla</subject><subject>Axillary lymph node dissection</subject><subject>Axillary staging</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - therapy</subject><subject>Carcinoma, Ductal, Breast - pathology</subject><subject>Carcinoma, Ductal, Breast - therapy</subject><subject>Carcinoma, Intraductal, Noninfiltrating - pathology</subject><subject>Carcinoma, Intraductal, Noninfiltrating - therapy</subject><subject>Carcinoma, Lobular - pathology</subject><subject>Carcinoma, Lobular - therapy</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Lymph Node Excision</subject><subject>Lymphatic Metastasis</subject><subject>Lymphatic system</subject><subject>Mammaplasty</subject><subject>Mastectomy</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Patients</subject><subject>Postmastectomy radiation</subject><subject>Radiotherapy, Adjuvant</subject><subject>Reconstruction</subject><subject>Sentinel Lymph Node Biopsy - methods</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Scott</au><au>Kim, Hong Jin</au><au>Meyers, Michael O.</au><au>Damitz, Lynn</au><au>Frank, Jill S.</au><au>Stitzenberg, Karen B.</au><au>Sartor, Carolyn I.</au><au>Ollila, David W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>2005-10-01</date><risdate>2005</risdate><volume>190</volume><issue>4</issue><spage>595</spage><epage>597</epage><pages>595-597</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><coden>AJSUAB</coden><abstract>In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures.
Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.
Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.
Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16164929</pmid><doi>10.1016/j.amjsurg.2005.06.020</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Aged Axilla Axillary lymph node dissection Axillary staging Biological and medical sciences Biopsy Breast cancer Breast Neoplasms - pathology Breast Neoplasms - therapy Carcinoma, Ductal, Breast - pathology Carcinoma, Ductal, Breast - therapy Carcinoma, Intraductal, Noninfiltrating - pathology Carcinoma, Intraductal, Noninfiltrating - therapy Carcinoma, Lobular - pathology Carcinoma, Lobular - therapy Female General aspects Humans Lymph Node Excision Lymphatic Metastasis Lymphatic system Mammaplasty Mastectomy Medical research Medical sciences Middle Aged Neoplasm Staging Patients Postmastectomy radiation Radiotherapy, Adjuvant Reconstruction Sentinel Lymph Node Biopsy - methods Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the genital tract and mammary gland Transverse rectus abdominis musculocutaneous delay |
title | Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients |
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