Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients

In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive oper...

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Veröffentlicht in:The American journal of surgery 2005-10, Vol.190 (4), p.595-597
Hauptverfasser: Klauber-DeMore, Nancy, Calvo, Benjamin F., Hultman, C. Scott, Kim, Hong Jin, Meyers, Michael O., Damitz, Lynn, Frank, Jill S., Stitzenberg, Karen B., Sartor, Carolyn I., Ollila, David W.
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container_issue 4
container_start_page 595
container_title The American journal of surgery
container_volume 190
creator Klauber-DeMore, Nancy
Calvo, Benjamin F.
Hultman, C. Scott
Kim, Hong Jin
Meyers, Michael O.
Damitz, Lynn
Frank, Jill S.
Stitzenberg, Karen B.
Sartor, Carolyn I.
Ollila, David W.
description In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures. Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004. Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander. Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction.
doi_str_mv 10.1016/j.amjsurg.2005.06.020
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The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures. Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004. Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander. 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subjects Adult
Aged
Axilla
Axillary lymph node dissection
Axillary staging
Biological and medical sciences
Biopsy
Breast cancer
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Carcinoma, Ductal, Breast - pathology
Carcinoma, Ductal, Breast - therapy
Carcinoma, Intraductal, Noninfiltrating - pathology
Carcinoma, Intraductal, Noninfiltrating - therapy
Carcinoma, Lobular - pathology
Carcinoma, Lobular - therapy
Female
General aspects
Humans
Lymph Node Excision
Lymphatic Metastasis
Lymphatic system
Mammaplasty
Mastectomy
Medical research
Medical sciences
Middle Aged
Neoplasm Staging
Patients
Postmastectomy radiation
Radiotherapy, Adjuvant
Reconstruction
Sentinel Lymph Node Biopsy - methods
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the genital tract and mammary gland
Transverse rectus abdominis musculocutaneous delay
title Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients
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