Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene
In this study, gelatin blended with arabic gum microcapsules containing camphor oil with added polystyrene were fabricated by a compound coacervation method. The parameters of oil/wall volume ratio, emulsification stirring speed, concentration of cross-linking agent, treated time and oil release pro...
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| Veröffentlicht in: | Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2006-07, Vol.50 (2), p.136-140 |
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| container_title | Colloids and surfaces, B, Biointerfaces |
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| creator | Chang, Chih-Pong Leung, Ting-Kai Lin, Shang-Ming Hsu, Che-Chang |
| description | In this study, gelatin blended with arabic gum microcapsules containing camphor oil with added polystyrene were fabricated by a compound coacervation method. The parameters of oil/wall volume ratio, emulsification stirring speed, concentration of cross-linking agent, treated time and oil release properties were investigated. In order to improve the constant release effect of camphor oil, oil-soluble polystyrene (PS) was used as a sustained release agent. The camphor oil release curves were expressed by the exponential equation:
ψ(
t)
=
C
eq(1–e
−
t/
τ
), where
ψ(
t) represent the variant of camphor oil concentration in the operation environment,
C
eq as the equilibrium state,
t as the release time and
τ as time constant.
C
eq and
τ are significant factors pertaining to the camphor oil release properties. The results indicated that, for the microcapsules, the optimal oil/wall volume ratio was 0.75 to achieve the encapsulation efficiency of 99.6
wt.%. The average particle size were 294.7
±
14.2
μm, 167.2
±
11.2
μm, 85.7
±
8.7
μm at the homogenization stirring speed of 500, 1000, and 2000
rpm, respectively. The effect of sustained oil release will increase whereas the stirring speed decreases and the concentration of glutaraldehyde (GA) and treated time increases. Along with the increasing of quantity of polystyrene added,
C
eq decreased and
τ increased, indicating that the sustained oil release amount and the release rate depend on the quantity of PS considerably. |
| doi_str_mv | 10.1016/j.colsurfb.2006.04.008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68589414</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0927776506001408</els_id><sourcerecordid>19450518</sourcerecordid><originalsourceid>FETCH-LOGICAL-c397t-acc09017e75b4e8e59b6118dc8eb8a199cbaaf9787ee82f39f1a339d9dc391e33</originalsourceid><addsrcrecordid>eNqFkU9r3DAUxEVoSTZ_vkLQqTc7ki1b0i1laZvAQqE0ZyFLzxstsuVIdsN--2jZLTnu6V1-84aZQeiekpIS2j7sShN8WmLflRUhbUlYSYi4QCsqeF2wuuVf0IrIihect80Vuk5pRwipGOWX6Iq2XHLJqhWyf8CDToCnGCaIs4OEw4i34PXsxmK7DFhH3TmDB2diMHpKi8-MCeOs3ejGLTZ6mF5DxMF5_O7mV6ytBYun4Pdp3kcY4RZ97bVPcHe6N-jl54-_66di8_vX8_r7pjC15HOhjSGSUA686RgIaGTXUiqsEdAJTaU0nda95IIDiKqvZU91XUsrbdZTqOsb9O34N4d5WyDNanDJgPd6hLAk1YpGSEbZWZBK1pCGigy2RzBnTylCr6boBh33ihJ1GELt1P8h1GEIRZjKQ2Th_clh6Qawn7JT8xl4PAKQC_nnIKpkHIwGrItgZmWDO-fxAc4CoBk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19450518</pqid></control><display><type>article</type><title>Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Chang, Chih-Pong ; Leung, Ting-Kai ; Lin, Shang-Ming ; Hsu, Che-Chang</creator><creatorcontrib>Chang, Chih-Pong ; Leung, Ting-Kai ; Lin, Shang-Ming ; Hsu, Che-Chang</creatorcontrib><description>In this study, gelatin blended with arabic gum microcapsules containing camphor oil with added polystyrene were fabricated by a compound coacervation method. The parameters of oil/wall volume ratio, emulsification stirring speed, concentration of cross-linking agent, treated time and oil release properties were investigated. In order to improve the constant release effect of camphor oil, oil-soluble polystyrene (PS) was used as a sustained release agent. The camphor oil release curves were expressed by the exponential equation:
ψ(
t)
=
C
eq(1–e
−
t/
τ
), where
ψ(
t) represent the variant of camphor oil concentration in the operation environment,
C
eq as the equilibrium state,
t as the release time and
τ as time constant.
C
eq and
τ are significant factors pertaining to the camphor oil release properties. The results indicated that, for the microcapsules, the optimal oil/wall volume ratio was 0.75 to achieve the encapsulation efficiency of 99.6
wt.%. The average particle size were 294.7
±
14.2
μm, 167.2
±
11.2
μm, 85.7
±
8.7
μm at the homogenization stirring speed of 500, 1000, and 2000
rpm, respectively. The effect of sustained oil release will increase whereas the stirring speed decreases and the concentration of glutaraldehyde (GA) and treated time increases. Along with the increasing of quantity of polystyrene added,
C
eq decreased and
τ increased, indicating that the sustained oil release amount and the release rate depend on the quantity of PS considerably.</description><identifier>ISSN: 0927-7765</identifier><identifier>EISSN: 1873-4367</identifier><identifier>DOI: 10.1016/j.colsurfb.2006.04.008</identifier><identifier>PMID: 16797942</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Biocompatible Materials ; Camphor - administration & dosage ; Camphor oil ; Capsules ; Complex coacervation method ; Delayed-Action Preparations ; Drug Compounding ; Gelatin ; Gum Arabic ; Materials Testing ; Microspheres ; Particle Size ; Plant Oils - administration & dosage ; Polystyrene ; Polystyrenes ; Sustained release</subject><ispartof>Colloids and surfaces, B, Biointerfaces, 2006-07, Vol.50 (2), p.136-140</ispartof><rights>2006 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c397t-acc09017e75b4e8e59b6118dc8eb8a199cbaaf9787ee82f39f1a339d9dc391e33</citedby><cites>FETCH-LOGICAL-c397t-acc09017e75b4e8e59b6118dc8eb8a199cbaaf9787ee82f39f1a339d9dc391e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.colsurfb.2006.04.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16797942$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chang, Chih-Pong</creatorcontrib><creatorcontrib>Leung, Ting-Kai</creatorcontrib><creatorcontrib>Lin, Shang-Ming</creatorcontrib><creatorcontrib>Hsu, Che-Chang</creatorcontrib><title>Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene</title><title>Colloids and surfaces, B, Biointerfaces</title><addtitle>Colloids Surf B Biointerfaces</addtitle><description>In this study, gelatin blended with arabic gum microcapsules containing camphor oil with added polystyrene were fabricated by a compound coacervation method. The parameters of oil/wall volume ratio, emulsification stirring speed, concentration of cross-linking agent, treated time and oil release properties were investigated. In order to improve the constant release effect of camphor oil, oil-soluble polystyrene (PS) was used as a sustained release agent. The camphor oil release curves were expressed by the exponential equation:
ψ(
t)
=
C
eq(1–e
−
t/
τ
), where
ψ(
t) represent the variant of camphor oil concentration in the operation environment,
C
eq as the equilibrium state,
t as the release time and
τ as time constant.
C
eq and
τ are significant factors pertaining to the camphor oil release properties. The results indicated that, for the microcapsules, the optimal oil/wall volume ratio was 0.75 to achieve the encapsulation efficiency of 99.6
wt.%. The average particle size were 294.7
±
14.2
μm, 167.2
±
11.2
μm, 85.7
±
8.7
μm at the homogenization stirring speed of 500, 1000, and 2000
rpm, respectively. The effect of sustained oil release will increase whereas the stirring speed decreases and the concentration of glutaraldehyde (GA) and treated time increases. Along with the increasing of quantity of polystyrene added,
C
eq decreased and
τ increased, indicating that the sustained oil release amount and the release rate depend on the quantity of PS considerably.</description><subject>Biocompatible Materials</subject><subject>Camphor - administration & dosage</subject><subject>Camphor oil</subject><subject>Capsules</subject><subject>Complex coacervation method</subject><subject>Delayed-Action Preparations</subject><subject>Drug Compounding</subject><subject>Gelatin</subject><subject>Gum Arabic</subject><subject>Materials Testing</subject><subject>Microspheres</subject><subject>Particle Size</subject><subject>Plant Oils - administration & dosage</subject><subject>Polystyrene</subject><subject>Polystyrenes</subject><subject>Sustained release</subject><issn>0927-7765</issn><issn>1873-4367</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9r3DAUxEVoSTZ_vkLQqTc7ki1b0i1laZvAQqE0ZyFLzxstsuVIdsN--2jZLTnu6V1-84aZQeiekpIS2j7sShN8WmLflRUhbUlYSYi4QCsqeF2wuuVf0IrIihect80Vuk5pRwipGOWX6Iq2XHLJqhWyf8CDToCnGCaIs4OEw4i34PXsxmK7DFhH3TmDB2diMHpKi8-MCeOs3ejGLTZ6mF5DxMF5_O7mV6ytBYun4Pdp3kcY4RZ97bVPcHe6N-jl54-_66di8_vX8_r7pjC15HOhjSGSUA686RgIaGTXUiqsEdAJTaU0nda95IIDiKqvZU91XUsrbdZTqOsb9O34N4d5WyDNanDJgPd6hLAk1YpGSEbZWZBK1pCGigy2RzBnTylCr6boBh33ihJ1GELt1P8h1GEIRZjKQ2Th_clh6Qawn7JT8xl4PAKQC_nnIKpkHIwGrItgZmWDO-fxAc4CoBk</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Chang, Chih-Pong</creator><creator>Leung, Ting-Kai</creator><creator>Lin, Shang-Ming</creator><creator>Hsu, Che-Chang</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene</title><author>Chang, Chih-Pong ; Leung, Ting-Kai ; Lin, Shang-Ming ; Hsu, Che-Chang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-acc09017e75b4e8e59b6118dc8eb8a199cbaaf9787ee82f39f1a339d9dc391e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biocompatible Materials</topic><topic>Camphor - administration & dosage</topic><topic>Camphor oil</topic><topic>Capsules</topic><topic>Complex coacervation method</topic><topic>Delayed-Action Preparations</topic><topic>Drug Compounding</topic><topic>Gelatin</topic><topic>Gum Arabic</topic><topic>Materials Testing</topic><topic>Microspheres</topic><topic>Particle Size</topic><topic>Plant Oils - administration & dosage</topic><topic>Polystyrene</topic><topic>Polystyrenes</topic><topic>Sustained release</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chang, Chih-Pong</creatorcontrib><creatorcontrib>Leung, Ting-Kai</creatorcontrib><creatorcontrib>Lin, Shang-Ming</creatorcontrib><creatorcontrib>Hsu, Che-Chang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Colloids and surfaces, B, Biointerfaces</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chang, Chih-Pong</au><au>Leung, Ting-Kai</au><au>Lin, Shang-Ming</au><au>Hsu, Che-Chang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene</atitle><jtitle>Colloids and surfaces, B, Biointerfaces</jtitle><addtitle>Colloids Surf B Biointerfaces</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>50</volume><issue>2</issue><spage>136</spage><epage>140</epage><pages>136-140</pages><issn>0927-7765</issn><eissn>1873-4367</eissn><abstract>In this study, gelatin blended with arabic gum microcapsules containing camphor oil with added polystyrene were fabricated by a compound coacervation method. The parameters of oil/wall volume ratio, emulsification stirring speed, concentration of cross-linking agent, treated time and oil release properties were investigated. In order to improve the constant release effect of camphor oil, oil-soluble polystyrene (PS) was used as a sustained release agent. The camphor oil release curves were expressed by the exponential equation:
ψ(
t)
=
C
eq(1–e
−
t/
τ
), where
ψ(
t) represent the variant of camphor oil concentration in the operation environment,
C
eq as the equilibrium state,
t as the release time and
τ as time constant.
C
eq and
τ are significant factors pertaining to the camphor oil release properties. The results indicated that, for the microcapsules, the optimal oil/wall volume ratio was 0.75 to achieve the encapsulation efficiency of 99.6
wt.%. The average particle size were 294.7
±
14.2
μm, 167.2
±
11.2
μm, 85.7
±
8.7
μm at the homogenization stirring speed of 500, 1000, and 2000
rpm, respectively. The effect of sustained oil release will increase whereas the stirring speed decreases and the concentration of glutaraldehyde (GA) and treated time increases. Along with the increasing of quantity of polystyrene added,
C
eq decreased and
τ increased, indicating that the sustained oil release amount and the release rate depend on the quantity of PS considerably.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>16797942</pmid><doi>10.1016/j.colsurfb.2006.04.008</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0927-7765 |
| ispartof | Colloids and surfaces, B, Biointerfaces, 2006-07, Vol.50 (2), p.136-140 |
| issn | 0927-7765 1873-4367 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Biocompatible Materials Camphor - administration & dosage Camphor oil Capsules Complex coacervation method Delayed-Action Preparations Drug Compounding Gelatin Gum Arabic Materials Testing Microspheres Particle Size Plant Oils - administration & dosage Polystyrene Polystyrenes Sustained release |
| title | Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene |
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