Gene Promoter Methylation in Plasma and Sputum Increases with Lung Cancer Risk

Purpose: Lung cancer is the leading cause of cancer mortality in the United States, due in part to the lack of a validated and effective screening approach for early detection. The prevalence for methylation of seven and three genes was examined in DNA from sputum and plasma, respectively, from wome...

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Veröffentlicht in:Clinical cancer research 2005-09, Vol.11 (18), p.6505-6511
Hauptverfasser: BELINSKY, Steven A, KLINGE, Donna M, DEKKER, Joseph D, SMITH, Mitzi W, BOCKLAGE, Theresa J, GILLILAND, Frank D, CROWELL, Richard E, KARP, Daniel D, STIDLEY, Christine A, PICCHI, Maria A
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Sprache:eng
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