Topiramate: a prospective study on the relationship between concentration, dosage and adverse events in epileptic patients on combination therapy

The relationship between topiramate (TPM) concentration, dosage and adverse events in patients with epilepsy is still controversial. We therefore performed a prospective study in patients with poorly controlled epilepsy treated with TPM, predominantly in combination with other antiepileptic drugs. T...

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Veröffentlicht in:	Epileptic disorders 2005-09, Vol.7 (3), p.237-248
Hauptverfasser:	Fröscher, Walter, Schier, Katja R, Hoffmann, Markus, Meyer, Andreas, May, Theodor W, Rambeck, Bernhard, Rösche, Johannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anticonvulsants - administration & dosage Anticonvulsants - blood Cognition - drug effects Dose-Response Relationship, Drug Drug Therapy, Combination Epilepsy - drug therapy Female Fructose - administration & dosage Fructose - analogs & derivatives Fructose - blood Humans Logistic Models Male Middle Aged Prospective Studies
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