Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma

While most osteosarcoma patients have metastatic or micrometastatic lesions, less than 15% of them have clinically detectable metastatic diseases at presentation. To identify potential markers that may predict osteosarcoma metastasis, we analyzed the expression of S100A6 in 50 osteosarcoma cases and...

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Veröffentlicht in:	Cancer letters 2005-11, Vol.229 (1), p.135-148
Hauptverfasser:	Luu, Hue H., Zhou, Lan, Haydon, Rex C., Deyrup, Andrea T., Montag, Anthony G., Huo, Dezheng, Heck, Robert, Heizmann, Claus W., Peabody, Terrance D., Simon, Michael A., He, Tong-Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anchorage independent growth Bone Neoplasms - genetics Bone Neoplasms - pathology Breast cancer Cell Adhesion Cell Cycle Proteins - biosynthesis Cell Cycle Proteins - physiology Cell motility Cell Movement Chemotherapy Colleges & universities EF-hand proteins Female Gastric cancer Gene Expression Profiling Humans Immunohistochemistry Male Melanoma Metastasis Motility Neoplasm Metastasis - genetics Osteosarcoma Osteosarcoma - genetics Osteosarcoma - pathology Phenotype Proteins S100 Calcium Binding Protein A6 S100 Proteins - biosynthesis S100 Proteins - physiology S100A6 Survival Analysis Tumor Cells, Cultured Tumors
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