Newly born granule cells in the dentate gyrus rapidly extend axons into the hippocampal CA3 region following experimental brain injury

We investigated whether new neurons generated in the adult rat brain following lateral fluid percussion traumatic brain injury (TBI) are capable of projecting axons along the mossy fiber pathway to the CA3 region of the hippocampus. Dividing cells were labeled by intraperitoneal injection of bromode...

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Veröffentlicht in:	Journal of neurotrauma 2005-09, Vol.22 (9), p.978-988
Hauptverfasser:	Emery, Dana L, Fulp, Carl T, Saatman, Kathryn E, Schütz, Christian, Neugebauer, Edmund, McIntosh, Tracy K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - metabolism Axons - pathology Brain damage Brain Injuries - pathology Bromodeoxyuridine Cellular biology Dentate Gyrus - cytology Dentate Gyrus - metabolism Dentate Gyrus - pathology Disease Models, Animal Hippocampus - cytology Hippocampus - metabolism Hippocampus - pathology Immunohistochemistry Male Nerve Regeneration - physiology Neural Cell Adhesion Molecule L1 - metabolism Neural Pathways - cytology Neural Pathways - metabolism Neurosciences Rats Rats, Sprague-Dawley Rodents Sialic Acids - metabolism
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