Nature: A rich source for developing multifunctional agents. tumor-imaging and photodynamic therapy
The purpose of this review is to call attention in the use of chlorophyll‐a and bacteriochlorophyll‐a to develop more than 600 photosensitizers (λ max 660 nm–800 nm) during the last 15 years (1990–2005) at the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo. This article mainly i...
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| Veröffentlicht in: | Lasers in surgery and medicine 2006-06, Vol.38 (5), p.445-467 |
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| container_issue | 5 |
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| container_title | Lasers in surgery and medicine |
| container_volume | 38 |
| creator | Pandey, Ravindra K. Goswami, Lalit N. Chen, Yihui Gryshuk, Amy Missert, Joseph R. Oseroff, Allan Dougherty, Thomas J. |
| description | The purpose of this review is to call attention in the use of chlorophyll‐a and bacteriochlorophyll‐a to develop more than 600 photosensitizers (λ max 660 nm–800 nm) during the last 15 years (1990–2005) at the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo. This article mainly includes the chemistry, preclinical results, and brief clinical data of some of the most effective photosensitizers. The utility of the tumor‐avid photosensitizers in developing multimodality agents (imaging and therapy) is also presented. Lasers Surg. Med. 38:445–467, 2006. © 2006 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/lsm.20352 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Lasers in surgery and medicine, 2006-06, Vol.38 (5), p.445-467 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | age related macular degeneration Bacteriochlorophyll A - chemistry Bacteriochlorophyll A - pharmacology Chlorophyll - chemistry Chlorophyll - pharmacology Diagnostic Imaging fluoro-deoxyglucose fluoro‐deoxyglucose, MRI, PET, PDT Fullerenes Humans MRI Neoplasms - drug therapy Neoplasms - pathology PDT PET Photochemotherapy Photosensitizing Agents - chemistry Photosensitizing Agents - pharmacology |
| title | Nature: A rich source for developing multifunctional agents. tumor-imaging and photodynamic therapy |
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