Neutrophil serine proteases: specific regulators of inflammation

Key Points The neutrophil serine proteases cathepsin G, neutrophil elastase and proteinase 3 are structurally related enzymes that are stored in their active form in the azurophil granules of neutrophils. They are synthesized during the pro-myelocytic stage of neutrophil differentiation as inactive...

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Veröffentlicht in:	Nature Reviews: Immunology 2006-07, Vol.6 (7), p.541-550
1. Verfasser:	Pham, Christine T. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial agents Biomedicine Enzymes Humans Immunology Infection - immunology Inflammation Inflammation - enzymology Inflammation - immunology Inflammation - microbiology Mice Microorganisms Models, Immunological Neutrophils Neutrophils - enzymology Pathogens Peptides Proteins review-article Serine Endopeptidases - immunology Weapons
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