Association Between Serum Beta-Carotene Levels and Decline of Cognitive Function in High-Functioning Older Persons With or Without Apolipoprotein E 4 Alleles: MacArthur Studies of Successful Aging

Background. Growing evidence from animal studies suggests an interaction between antioxidants and apolipoprotein E (APOE) alleles on cognitive functioning. We used data from a 7-year cohort study of high-functioning older persons to explore whether the associations between serum beta-carotene level...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2006-06, Vol.61 (6), p.616-620
Hauptverfasser:	Hu, Peifeng, Bretsky, Philip, Crimmins, Eileen M., Guralnik, Jack M., Reuben, David B., Seeman, Teresa E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Aged Aging Aging - physiology Alleles Apolipoprotein E4 Apolipoproteins E - blood Apolipoproteins E - genetics beta Carotene - blood Biomarkers - blood Cognition & reasoning Cognition Disorders - blood Cognition Disorders - genetics Enzyme-Linked Immunosorbent Assay Female Follow-Up Studies Genotype Humans Male Nutrition Older people Proteins Retrospective Studies Risk Factors Vitamin A
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