Endocrinology – The way we were: A personal history of somatomedin
Fifty years ago there was no practical method for measuring growth hormone (GH) activity in human plasma. In an attempt to develop such an assay, it was determined that much of the action of GH in vivo on rat cartilage was mediated by a serum factor that was first known as sulfation factor, and late...
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| Veröffentlicht in: | Growth hormone & IGF research 2006-07, Vol.16, p.3-5 |
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| creator | Daughaday, William H. |
| description | Fifty years ago there was no practical method for measuring growth hormone (GH) activity in human plasma. In an attempt to develop such an assay, it was determined that much of the action of GH in vivo on rat cartilage was mediated by a serum factor that was first known as
sulfation factor, and later as
somatomedin and
insulin-like growth factor. This narrative describes my experience and that of others in this important area of endocrine research. |
| doi_str_mv | 10.1016/j.ghir.2006.03.005 |
| format | Article |
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sulfation factor, and later as
somatomedin and
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sulfation factor, and later as
somatomedin and
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somatomedin and
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| fulltext | fulltext |
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| ispartof | Growth hormone & IGF research, 2006-07, Vol.16, p.3-5 |
| issn | 1096-6374 1532-2238 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Assays Cattle Child Endocrinology - history History, 20th Century History, 21st Century Humans Insulin-like growth factors Rats Somatomedin Somatomedins - history Sulfation factor |
| title | Endocrinology – The way we were: A personal history of somatomedin |
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