Antiproliferative Activity of Pteleopsis suberosa Leaf Extract and its Flavonoid Components in Human Prostate Carcinoma Cells

Abstract In this work we describe the chemical composition of PTELEOPSIS SUBEROSA (Combretaceae) leaf extract and its biological activity against androgen-insensitive human prostate cancer cells (DU-145). The methanol extract of the plant leaves exhibited activity against tumor cell growth. Fraction...

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Veröffentlicht in:	Planta medica 2006-06, Vol.72 (7), p.604-610
Hauptverfasser:	De Leo, M, Braca, A, Sanogo, R, Cardile, V, DeTommasi, N, Russo, A
Format:	Artikel
Sprache:	eng
Schlagworte:	anticarcinogenic activity apoptosis Biological and medical sciences Carcinoma - drug therapy Carcinoma - pathology caspase Caspase 3 Caspases - drug effects Cell Line, Tumor Cell Membrane - drug effects cell proliferation Cell Proliferation - drug effects chemical structure Combretaceae Combretaceae - chemistry cultured cells cytotoxicity DNA Fragmentation - drug effects flavonoids Flavonoids - chemistry General pharmacology Humans Male Medical sciences Molecular Structure myricetin Original Paper Oxidative Stress - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy plant extracts Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves - chemistry prostatic neoplasms Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Pteleopsis suberosa redox reactions signal transduction
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