Off limits – Integrins holding boundaries in somitogenesis

Borders are essential for demarcating repeated structures such as somites during vertebrate development. Two recent articles describe roles for Integrinα5 and its ligand Fibronectin1 in zebrafish anterior intersomitic boundary formation and link them to Notch and Eph–Ephrin pathways in epithelializa...

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Veröffentlicht in:	Trends in cell biology 2005-09, Vol.15 (9), p.453-457
Hauptverfasser:	Chong, Shang-Wei, Jiang, Yun-Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ephrins - physiology Epithelium - embryology Fibronectins - physiology Homeodomain Proteins - physiology Integrin alpha5 - physiology Integrins - physiology Nerve Tissue Proteins - physiology Receptor, Notch1 - physiology Receptors, Eph Family - physiology Somites - physiology Zebrafish - embryology Zebrafish Proteins - physiology
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