Evolutionary Implications of Bacterial Polyketide Synthases

Polyketide synthases (PKS) perform a stepwise biosynthesis of diverse carbon skeletons from simple activated carboxylic acid units. The products of the complex pathways possess a wide range of pharmaceutical properties, including antibiotic, antitumor, antifungal, and immunosuppressive activities. W...

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Veröffentlicht in:	Molecular biology and evolution 2005-10, Vol.22 (10), p.2027-2039
Hauptverfasser:	Jenke-Kodama, Holger, Sandmann, Axel, Müller, Rolf, Dittmann, Elke
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteria - classification Bacteria - enzymology Bacteria - genetics Bacterial Proteins - chemistry Bacterial Proteins - genetics Genome, Bacterial Phylogeny Polyketide Synthases - chemistry Polyketide Synthases - genetics Sequence Alignment Sequence Homology, Amino Acid
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