Stromal cell-derived factor-1alpha improves infarcted heart function through angiogenesis in mice

Local delivery of stromal cell-derived factor-1alpha (SDF-1) has been demonstrated to improve hind limb ischemia through enhanced neovascularization in animals. It was hypothesized that local administration of SDF-1 also contributes to neovascularization of ischemic heart. Acute myocardial infarctio...

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Veröffentlicht in:	Pediatrics international 2007-12, Vol.49 (6), p.966-971
Hauptverfasser:	Sasaki, Takashi, Fukazawa, Ryuji, Ogawa, Shunichi, Kanno, Shigeto, Nitta, Takashi, Ochi, Masami, Shimizu, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Capillaries - drug effects Capillaries - growth & development Chemokine CXCL12 - pharmacology Chemokine CXCL12 - therapeutic use Disease Models, Animal Echocardiography Ligation Mice Mice, Inbred C57BL Myocardial Infarction - drug therapy Myocardial Infarction - pathology Myocardial Infarction - physiopathology Myocardium - pathology Neovascularization, Physiologic - drug effects
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