Characterization of 6q abnormalities in childhood acute myeloid leukemia and identification of a novel t(6;11)(q24.1;p15.5) resulting in a NUP98-C6orf80 fusion in a case of acute megakaryoblastic leukemia

Chromosome abnormalities of 6q are not frequently observed in myeloid disorders. In this article, we report the incidence of these chromosome changes in childhood myeloid leukemia as 2%–4% based on the cytogenetic database of a single institution. We applied fluorescence in situ hybridization (FISH)...

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Veröffentlicht in:Genes chromosomes & cancer 2005-11, Vol.44 (3), p.225-232
Hauptverfasser: Tosi, Sabrina, Ballabio, Erica, Teigler-Schlegel, Andrea, Boultwood, Jackie, Bruch, Jochen, Harbott, Jochen
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Sprache:eng
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