Expression and Potential Role of Fibroblast Growth Factor 2 and Its Receptors in Human Embryonic Stem Cells

Although the detection of several components of the fibroblast growth factor (FGF) signaling pathway in human embryonic stem cells (hESCs) has been reported, the functionality of that pathway and effects on cell fate decisions are yet to be established. In this study we characterized expression of F...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2005-09, Vol.23 (8), p.1200-1211
Hauptverfasser:	Dvorak, Petr, Dvorakova, Dana, Koskova, Stanislava, Vodinska, Martina, Najvirtova, Miroslava, Krekac, Daniel, Hampl, Ales
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cell signaling Differentiation Dose-Response Relationship, Drug Embryo, Mammalian - cytology Fibroblast Growth Factor 2 - biosynthesis Fibroblast Growth Factor 2 - physiology Growth factor Human embryonic stem cells Humans Mitogen-Activated Protein Kinases - metabolism Phosphorylation Protein Isoforms Pyrroles - pharmacology Receptor, Fibroblast Growth Factor, Type 2 - biosynthesis Receptor, Fibroblast Growth Factor, Type 2 - physiology Receptors, Fibroblast Growth Factor - biosynthesis Receptors, Fibroblast Growth Factor - physiology Signal Transduction - physiology Stem Cells - cytology Stem Cells - drug effects Stem Cells - metabolism
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