The CCAAT-binding complex of eukaryotes: evolution of a second NLS in the HapB subunit of the filamentous fungus Aspergillus nidulans despite functional conservation at the molecular level between yeast, A.nidulans and human

The heterotrimeric CCAAT-binding complex is evolutionarily conserved in eukaryotic organisms, including fungi, plants and mammals. In the filamentous fungus Aspergillus nidulans, the corresponding complex was designated AnCF (A.nidulans CCAAT-binding factor). AnCF consists of the subunits HapB, HapC...

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Veröffentlicht in:	Journal of molecular biology 2005-09, Vol.352 (3), p.517-533
Hauptverfasser:	Tüncher, André, Spröte, Petra, Gehrke, Alexander, Brakhage, Axel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Aspergillus nidulans Aspergillus nidulans - chemistry Aspergillus nidulans - genetics Base Sequence CCAAT-Binding Factor - chemistry CCAAT-Binding Factor - genetics CCAAT-Binding Factor - metabolism Cell Nucleus - metabolism Conserved Sequence DNA, Fungal - genetics Evolution, Molecular Fungal Proteins - chemistry Fungal Proteins - genetics Fungal Proteins - metabolism Gene Deletion Genes, Fungal Genetic Complementation Test Green Fluorescent Proteins - chemistry Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Humans In Vitro Techniques Molecular Sequence Data Mutation Nuclear Localization Signals - genetics Protein Subunits Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Sequence Homology, Amino Acid Species Specificity
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