Dominant role of the GluR2 subunit in regulation of AMPA receptors by CaMKII

GluR1 and GluR2 subunits compose AMPA receptors (AMPARs) in the mature hippocampus, and both the GluR1 subunit and Ca2+/calmodulin-dependent protein kinase II (CaMKII) are required for synaptic plasticity, memory and learning. Although GluR1 phosphorylation by CaMKII is preserved, the functional reg...

Ausführliche Beschreibung