Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer
Background: The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O‐POSSUM). Methods: Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for a...
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Veröffentlicht in: | British journal of surgery 2007-12, Vol.94 (12), p.1521-1526 |
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container_title | British journal of surgery |
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creator | Lagarde, S. M. Maris, A. K. D. de Castro, S. M. M. Busch, O. R. C. Obertop, H. van Lanschot, J. J. B. |
description | Background:
The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O‐POSSUM).
Methods:
Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in‐hospital mortality predicted by O‐POSSUM was compared with the actual value by linear analysis.
Results:
Twenty‐four (3·6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in‐hospital mortality was 0·29. The model had a poor fit (P < 0·001). The area under the receiver–operator characteristic curve was 0·60 (95 per cent confidence interval 0·47 to 0·72); P = 0·113). O‐POSSUM score was not related to the severity of complications.
Conclusion:
O‐POSSUM overpredicted in‐hospital mortality threefold and could not identify patients at higher risk of death. O‐POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres. Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No value for comparative audits |
doi_str_mv | 10.1002/bjs.5850 |
format | Article |
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The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O‐POSSUM).
Methods:
Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in‐hospital mortality predicted by O‐POSSUM was compared with the actual value by linear analysis.
Results:
Twenty‐four (3·6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in‐hospital mortality was 0·29. The model had a poor fit (P < 0·001). The area under the receiver–operator characteristic curve was 0·60 (95 per cent confidence interval 0·47 to 0·72); P = 0·113). O‐POSSUM score was not related to the severity of complications.
Conclusion:
O‐POSSUM overpredicted in‐hospital mortality threefold and could not identify patients at higher risk of death. O‐POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres. Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No value for comparative audits</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.5850</identifier><identifier>PMID: 17929231</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Adenocarcinoma - mortality ; Adenocarcinoma - surgery ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - surgery ; Esophageal Neoplasms - mortality ; Esophageal Neoplasms - surgery ; Esophagectomy - mortality ; Female ; General aspects ; Hospital Mortality ; Humans ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Predictive Value of Tests ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Severity of Illness Index</subject><ispartof>British journal of surgery, 2007-12, Vol.94 (12), p.1521-1526</ispartof><rights>Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><rights>2008 INIST-CNRS</rights><rights>Copyright (c) 2007 British Journal of Surgery Society Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3880-b0bec9bbb7c795c5b70ad15b81cd72176e838a1e6fc167d47c1f12250462197e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.5850$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.5850$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19869644$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17929231$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lagarde, S. M.</creatorcontrib><creatorcontrib>Maris, A. K. D.</creatorcontrib><creatorcontrib>de Castro, S. M. M.</creatorcontrib><creatorcontrib>Busch, O. R. C.</creatorcontrib><creatorcontrib>Obertop, H.</creatorcontrib><creatorcontrib>van Lanschot, J. J. B.</creatorcontrib><title>Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O‐POSSUM).
Methods:
Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in‐hospital mortality predicted by O‐POSSUM was compared with the actual value by linear analysis.
Results:
Twenty‐four (3·6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in‐hospital mortality was 0·29. The model had a poor fit (P < 0·001). The area under the receiver–operator characteristic curve was 0·60 (95 per cent confidence interval 0·47 to 0·72); P = 0·113). O‐POSSUM score was not related to the severity of complications.
Conclusion:
O‐POSSUM overpredicted in‐hospital mortality threefold and could not identify patients at higher risk of death. O‐POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres. Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No value for comparative audits</description><subject>Adenocarcinoma - mortality</subject><subject>Adenocarcinoma - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Esophageal Neoplasms - mortality</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Esophagectomy - mortality</subject><subject>Female</subject><subject>General aspects</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Predictive Value of Tests</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Severity of Illness Index</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0ctO4zAUBmALDYJykeYJRtnM7AK-xJcsAXFVmY4oiKVlOydgSOOMnQJ9e1IodPXryJ-PZP8I_ST4gGBMD-1TOuCK4w00IkzwnBKhfqARxljmhFG2jXZSesKYMMzpFtomsqQlZWSEzOmLaeam96HNQp1N8n-T6fTuOvNt1kWovOt9-zBM-WNIne9Nk81CHML3i8zUPcQsQgL3cb8OMQuQQvdoHmCQzrQO4h7arE2TYH-Vu-ju7PT25CIfT84vT47GuWNK4dxiC6601konS-64ldhUhFtFXCUpkQIUU4aAqB0RsiqkIzWhlONCUFJKYLvoz-feLob_c0i9nvnkoGlMC2GetFCclYVUA_y1gnM7g0p30c9MXOivTxnA7xUwyZmmjsM7fFq7UolSFMXg8k_36htYrM-xXpaih1L0shR9fDVd5tr71MPbtzfxWQvJJNf3f8_1_Q2eqpvbsRbsHb8cjUk</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Lagarde, S. M.</creator><creator>Maris, A. K. D.</creator><creator>de Castro, S. M. M.</creator><creator>Busch, O. R. C.</creator><creator>Obertop, H.</creator><creator>van Lanschot, J. J. B.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200712</creationdate><title>Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer</title><author>Lagarde, S. M. ; Maris, A. K. D. ; de Castro, S. M. M. ; Busch, O. R. C. ; Obertop, H. ; van Lanschot, J. J. B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3880-b0bec9bbb7c795c5b70ad15b81cd72176e838a1e6fc167d47c1f12250462197e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adenocarcinoma - mortality</topic><topic>Adenocarcinoma - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Esophageal Neoplasms - mortality</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Esophagectomy - mortality</topic><topic>Female</topic><topic>General aspects</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Predictive Value of Tests</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Severity of Illness Index</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lagarde, S. M.</creatorcontrib><creatorcontrib>Maris, A. K. D.</creatorcontrib><creatorcontrib>de Castro, S. M. M.</creatorcontrib><creatorcontrib>Busch, O. R. C.</creatorcontrib><creatorcontrib>Obertop, H.</creatorcontrib><creatorcontrib>van Lanschot, J. J. B.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lagarde, S. M.</au><au>Maris, A. K. D.</au><au>de Castro, S. M. M.</au><au>Busch, O. R. C.</au><au>Obertop, H.</au><au>van Lanschot, J. J. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2007-12</date><risdate>2007</risdate><volume>94</volume><issue>12</issue><spage>1521</spage><epage>1526</epage><pages>1521-1526</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O‐POSSUM).
Methods:
Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in‐hospital mortality predicted by O‐POSSUM was compared with the actual value by linear analysis.
Results:
Twenty‐four (3·6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in‐hospital mortality was 0·29. The model had a poor fit (P < 0·001). The area under the receiver–operator characteristic curve was 0·60 (95 per cent confidence interval 0·47 to 0·72); P = 0·113). O‐POSSUM score was not related to the severity of complications.
Conclusion:
O‐POSSUM overpredicted in‐hospital mortality threefold and could not identify patients at higher risk of death. O‐POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres. Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No value for comparative audits</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>17929231</pmid><doi>10.1002/bjs.5850</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adenocarcinoma - mortality Adenocarcinoma - surgery Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - surgery Esophageal Neoplasms - mortality Esophageal Neoplasms - surgery Esophagectomy - mortality Female General aspects Hospital Mortality Humans Male Medical sciences Middle Aged Miscellaneous Predictive Value of Tests Public health. Hygiene Public health. Hygiene-occupational medicine Severity of Illness Index |
title | Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer |
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