Noninvasive determination of fetal RHD status by examination of cell-free DNA in maternal plasma

BACKGROUND: Cell‐free fetal DNA in maternal plasma opens the way for routine risk‐free diagnosis of fetal D status of D– mothers. The focus was on accuracy of RHD typing and confirmation of fetal DNA in maternal plasma while RHD was not detected. STUDY DESIGN AND METHODS: Plasma DNA was extracted (b...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2005-09, Vol.45 (9), p.1473-1480
Hauptverfasser:	Brojer, E., Żupanska, B., Guz, K., Orziñska, A., Kaliñska, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Grouping and Crossmatching Blood Preservation Blood Specimen Collection Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone marrow, stem cells transplantation. Graft versus host reaction DNA - blood DNA - isolation & purification Female Fetal Blood Genotype Gynecology. Andrology. Obstetrics Humans Male Management. Prenatal diagnosis Maternal-Fetal Exchange Medical sciences Polymerase Chain Reaction - standards Polymorphism, Genetic Predictive Value of Tests Pregnancy Pregnancy. Fetus. Placenta Reproducibility of Results Rh-Hr Blood-Group System - blood Rh-Hr Blood-Group System - genetics Sex Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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