Stability of lyophilized and reconstituted plasma/albumin-free recombinant human factor VIII (ADVATE rAHF-PFM)

Traditionally the serum protein albumin has been used to stabilize lyophilized recombinant factor VIII (rFVIII) products. Advanced rFVIII products have now been developed that employ other stabilizers. ADVATE antihaemophilic factor (recombinant), plasma/albumin‐free method (rAHF‐PFM) utilizes trehal...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Haemophilia : the official journal of the World Federation of Hemophilia 2005-09, Vol.11 (5), p.492-496
Hauptverfasser:	Parti, R., Schoppmann, A., Lee, H., Yang, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry, Pharmaceutical Drug Stability factor VIII Factor VIII - chemistry Freeze Drying haemophilia A Humans Preservatives, Pharmaceutical recombinant proteins Recombinant Proteins - chemistry Serum Albumin stability Temperature
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!