Effects of point mutations in the cytidine deaminase domains of APOBEC3B on replication and hypermutation of hepatitis B virus in vitro

Department of Clinical Research, University Hospital Berne, Switzerland Correspondence Jobst Greeve j.greeve{at}vincenz.de APOBEC3 cytidine deaminases hypermutate hepatitis B virus (HBV) and inhibit its replication in vitro . Whether this inhibition is due to the generation of hypermutations or to a...

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Veröffentlicht in:	Journal of general virology 2007-12, Vol.88 (12), p.3270-3274
Hauptverfasser:	Bonvin, Marianne, Greeve, Jobst
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line, Tumor Cytidine Deaminase - chemistry Cytidine Deaminase - genetics Fundamental and applied biological sciences. Psychology Hepatitis B - immunology Hepatitis B - virology Hepatitis B virus Hepatitis B virus - physiology Humans Microbiology Minor Histocompatibility Antigens Miscellaneous Mutation Protein Structure, Tertiary - genetics Virology Virus Replication
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