Improved Myocardial Function After Cold Storage With Preservation Solution Supplemented With a Carbon Monoxide–Releasing Molecule (CORM-3)

Background Carbon monoxide–releasing molecules (CO-RMs) are pharmacologically active as they protect against cardiac graft rejection and cold ischemia–mediated renal dysfunction. We investigated the cardioprotective role of carbon monoxide (CO) released from CORM-3 against cold ischemia–mediated inj...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2007-11, Vol.26 (11), p.1192-1198
Hauptverfasser:	Musameh, Muntaser D., MD, Green, Colin J., PhD, DSc, Mann, Brian E., PhD, Fuller, Barry J., PhD, DSc, Motterlini, Roberto, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carbon Monoxide Cold Ischemia - adverse effects Cold Ischemia - methods Creatine Kinase - metabolism Cryopreservation - methods Graft Rejection - prevention & control Heart - drug effects Heart - physiology Heart Transplantation - methods L-Lactate Dehydrogenase - metabolism Male Medical sciences Models, Animal Myocardium - enzymology Organ Preservation - methods Organ Preservation Solutions - pharmacology Organometallic Compounds - pharmacology Rats Rats, Inbred Lew Reperfusion Injury - prevention & control Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart
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