Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo

Erythropoietin (EPO) is a hormone that is currently used to treat patients with renal failure and anaemia. However, it has also been shown to protect against ischaemia/reperfusion injury; this protection occurring via activation of the ERK 1/2 and PI3K pathways. Since we have previously shown activa...

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Veröffentlicht in:	Basic research in cardiology 2005-09, Vol.100 (5), p.397-403
Hauptverfasser:	Bullard, A J, Govewalla, P, Yellon, D M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Erythropoiesis - drug effects Erythropoietin - therapeutic use Extracellular Signal-Regulated MAP Kinases - physiology In Vitro Techniques Male Myocardial Infarction - drug therapy Myocardial Reperfusion Injury - prevention & control Phosphatidylinositol 3-Kinases - physiology Rats Rats, Sprague-Dawley
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