Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition
Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we...
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| Veröffentlicht in: | Journal (Canadian Dental Association) 2007-11, Vol.73 (9), p.845-850 |
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| container_issue | 9 |
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| container_title | Journal (Canadian Dental Association) |
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| creator | DuVal, Marc G Davidson, Sarah Ho, Andrew Cohen, Rachale Park, Michael Nourian, Somayeh Baker, Gerald Sándor, George K B |
| description | Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potential role of an inhibitor of bone formation such as fetuin in preventing recurrence of aberrant ossification. |
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Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potential role of an inhibitor of bone formation such as fetuin in preventing recurrence of aberrant ossification.</description><identifier>ISSN: 0709-8936</identifier><identifier>EISSN: 1488-2159</identifier><identifier>PMID: 18028761</identifier><language>eng</language><publisher>Canada: Canadian Dental Assn</publisher><subject>Adolescent ; alpha-Fetoproteins - physiology ; Ankylosis - etiology ; Bone diseases ; Bone Morphogenetic Proteins - metabolism ; Dental care ; Dentistry ; Fibrous Dysplasia, Polyostotic - complications ; Genetic disorders ; Humans ; Male ; Masticatory Muscles - physiopathology ; Maxillofacial Abnormalities - etiology ; Medical research ; Ossification, Heterotopic - etiology ; Ossification, Heterotopic - prevention & control ; Osteogenesis - physiology ; Pseudopseudohypoparathyroidism - complications ; Temporomandibular Joint Disorders - etiology ; Transforming Growth Factor beta1 - metabolism</subject><ispartof>Journal (Canadian Dental Association), 2007-11, Vol.73 (9), p.845-850</ispartof><rights>Copyright Canadian Dental Assn Nov 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18028761$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DuVal, Marc G</creatorcontrib><creatorcontrib>Davidson, Sarah</creatorcontrib><creatorcontrib>Ho, Andrew</creatorcontrib><creatorcontrib>Cohen, Rachale</creatorcontrib><creatorcontrib>Park, Michael</creatorcontrib><creatorcontrib>Nourian, Somayeh</creatorcontrib><creatorcontrib>Baker, Gerald</creatorcontrib><creatorcontrib>Sándor, George K B</creatorcontrib><title>Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition</title><title>Journal (Canadian Dental Association)</title><addtitle>J Can Dent Assoc</addtitle><description>Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potential role of an inhibitor of bone formation such as fetuin in preventing recurrence of aberrant ossification.</description><subject>Adolescent</subject><subject>alpha-Fetoproteins - physiology</subject><subject>Ankylosis - etiology</subject><subject>Bone diseases</subject><subject>Bone Morphogenetic Proteins - metabolism</subject><subject>Dental care</subject><subject>Dentistry</subject><subject>Fibrous Dysplasia, Polyostotic - complications</subject><subject>Genetic disorders</subject><subject>Humans</subject><subject>Male</subject><subject>Masticatory Muscles - physiopathology</subject><subject>Maxillofacial Abnormalities - etiology</subject><subject>Medical research</subject><subject>Ossification, Heterotopic - etiology</subject><subject>Ossification, Heterotopic - prevention & control</subject><subject>Osteogenesis - physiology</subject><subject>Pseudopseudohypoparathyroidism - complications</subject><subject>Temporomandibular Joint Disorders - etiology</subject><subject>Transforming Growth Factor beta1 - metabolism</subject><issn>0709-8936</issn><issn>1488-2159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1LxDAQhoMo7vrxFyR40FOhTdqk9bYsfoHgZe8lTSfbLGlTk9Td_it_ohHXi6cZXp55GGZO0DLLyzIhWVGdomXK0yopK8oW6ML7XZoSSqriHC2yMiUlZ9kSfa1M4_S2C_ced-Cg1UG4GVsfwLazD86O3Yz3OnQYDgEGrz8hggGcDXbUMpJeKy1F0HbAVuHQAbZOGCyGFvfioI2xSkgdEwfbCD3gzu6xgjDpIUYehJNdJOeoNSMW2AP0etiaGet-_NE3BrC0Q1wtjl-hMyWMh-tjvUSbp8fN-iV5e39-Xa_ekpFQFhJO85RDUzVty4CzFDJFY6PyAgrasJzJTEgomFC0oJwr0fAsA8h5W-ZSlfQS3f1qR2c_JvCh7rWXYIwYwE6-ZmVBCackgrf_wJ2d3BBXqwnJo7RiaYRujtDU9NDWo9N9PHP99wf6DYZ5itk</recordid><startdate>200711</startdate><enddate>200711</enddate><creator>DuVal, Marc G</creator><creator>Davidson, Sarah</creator><creator>Ho, Andrew</creator><creator>Cohen, Rachale</creator><creator>Park, Michael</creator><creator>Nourian, Somayeh</creator><creator>Baker, Gerald</creator><creator>Sándor, George K B</creator><general>Canadian Dental Assn</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200711</creationdate><title>Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition</title><author>DuVal, Marc G ; Davidson, Sarah ; Ho, Andrew ; Cohen, Rachale ; Park, Michael ; Nourian, Somayeh ; Baker, Gerald ; Sándor, George K B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p236t-73407eb9bdd6e760e1f36e7f45e53b646c1ace56af35377fab711ee47d84cf83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>alpha-Fetoproteins - physiology</topic><topic>Ankylosis - etiology</topic><topic>Bone diseases</topic><topic>Bone Morphogenetic Proteins - metabolism</topic><topic>Dental care</topic><topic>Dentistry</topic><topic>Fibrous Dysplasia, Polyostotic - complications</topic><topic>Genetic disorders</topic><topic>Humans</topic><topic>Male</topic><topic>Masticatory Muscles - physiopathology</topic><topic>Maxillofacial Abnormalities - etiology</topic><topic>Medical research</topic><topic>Ossification, Heterotopic - etiology</topic><topic>Ossification, Heterotopic - prevention & control</topic><topic>Osteogenesis - physiology</topic><topic>Pseudopseudohypoparathyroidism - complications</topic><topic>Temporomandibular Joint Disorders - etiology</topic><topic>Transforming Growth Factor beta1 - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DuVal, Marc G</creatorcontrib><creatorcontrib>Davidson, Sarah</creatorcontrib><creatorcontrib>Ho, Andrew</creatorcontrib><creatorcontrib>Cohen, Rachale</creatorcontrib><creatorcontrib>Park, Michael</creatorcontrib><creatorcontrib>Nourian, Somayeh</creatorcontrib><creatorcontrib>Baker, Gerald</creatorcontrib><creatorcontrib>Sándor, George K B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal (Canadian Dental Association)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DuVal, Marc G</au><au>Davidson, Sarah</au><au>Ho, Andrew</au><au>Cohen, Rachale</au><au>Park, Michael</au><au>Nourian, Somayeh</au><au>Baker, Gerald</au><au>Sándor, George K B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition</atitle><jtitle>Journal (Canadian Dental Association)</jtitle><addtitle>J Can Dent Assoc</addtitle><date>2007-11</date><risdate>2007</risdate><volume>73</volume><issue>9</issue><spage>845</spage><epage>850</epage><pages>845-850</pages><issn>0709-8936</issn><eissn>1488-2159</eissn><abstract>Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potential role of an inhibitor of bone formation such as fetuin in preventing recurrence of aberrant ossification.</abstract><cop>Canada</cop><pub>Canadian Dental Assn</pub><pmid>18028761</pmid><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0709-8936 |
| ispartof | Journal (Canadian Dental Association), 2007-11, Vol.73 (9), p.845-850 |
| issn | 0709-8936 1488-2159 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent alpha-Fetoproteins - physiology Ankylosis - etiology Bone diseases Bone Morphogenetic Proteins - metabolism Dental care Dentistry Fibrous Dysplasia, Polyostotic - complications Genetic disorders Humans Male Masticatory Muscles - physiopathology Maxillofacial Abnormalities - etiology Medical research Ossification, Heterotopic - etiology Ossification, Heterotopic - prevention & control Osteogenesis - physiology Pseudopseudohypoparathyroidism - complications Temporomandibular Joint Disorders - etiology Transforming Growth Factor beta1 - metabolism |
| title | Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition |
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