Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study
Background. This study examined the efficacy of craniofacial surgery (CFS) in treating locally advanced nonmelanoma skin cancer (NMSC). Methods. One hundred twenty patients who underwent CFS for NMSC were identified from 17 participating institutions. Patient, tumor, and treatment information was an...
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| Veröffentlicht in: | Head & neck 2007-12, Vol.29 (12), p.1136-1143 |
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| creator | Maghami, Ellie G. Talbot, Simon G. Patel, Snehal G. Singh, Bhuvanesh Polluri, Ashok Bridger, Patrick G. Cantu, Giulio Cheesman, Anthony D. Sa, Geraldo De Donald, Paul dos Santos, Luiz R. M. Fliss, Dan Gullane, Patrick Janecka, Ivo Kamata, Shin‐Etsu Kowalski, Luiz P. Kraus, Dennis H. Levine, Paul A. Pradhan, Sultan Schramm, Victor Snyderman, Carl Wei, William I. Shah, Jatin P. Wax, Mark L. |
| description | Background.
This study examined the efficacy of craniofacial surgery (CFS) in treating locally advanced nonmelanoma skin cancer (NMSC).
Methods.
One hundred twenty patients who underwent CFS for NMSC were identified from 17 participating institutions. Patient, tumor, and treatment information was analyzed for prognostic impact on survival.
Results.
Surgical margins were negative in 74%, close in 3%, and involved in 23% of patients. Complications occurred in 35% of patients, half of which were local wound problems. Operative mortality was 4%. Median follow‐up interval after CFS was 27 months. The 5‐year overall survival (OS), disease‐specific survival (DSS), and recurrence‐free survival (RFS) rates were 64%, 75%, and 60%, respectively. Squamous cell histology, brain invasion, and positive resection margins independently predicted worse OS, DSS, and RFS.
Conclusion.
CFS is an effective treatment for patients with NMSC invading the skull base. Histology, extent of disease, and resection margins are the most significant predictors of outcome. © 2007 Wiley Periodicals, Inc. Head Neck, 2007 |
| doi_str_mv | 10.1002/hed.20656 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68527035</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68527035</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3886-71f55791d1bca07eab0c5eeba65d14a35bc13a695b7111a6bcea925ba15888e03</originalsourceid><addsrcrecordid>eNp1kE1P3DAQhq0KVGDbQ_8A8oVKHAJ2HNtJb2ihBQkJCdFzNHYm1JDYWzspyr_HdFf01NN86NE7o4eQL5ydccbK81_YnZVMSfWBHHLW6IKJSu-99ZUoBNPVATlK6YkxJlRVfiQHXGtVsVodkm4dwbvQg3Uw0DTHR4wL7UOkPvgRB_BhBJqenacjDO7Rg7fLN3qPmxAnGnoKnjo_YfQwueBzhg3DACbEPP9Bmqa5Wz6R_R6GhJ93dUV-fr96WF8Xt3c_btYXt4UVda0KzXspdcM7biwwjWCYlYgGlOx4BUIaywWoRhrNOQdlLEJTSgNc1nWNTKzI123uJobfM6apHV2ymP_xGObUqlqWmgmZwdMtaGNIKWLfbqIbIS4tZ-2b0jYrbf8qzezxLnQ2Y96-kzuHGTjZAZAsDH0Wal36xzW1UlLozJ1vuRc34PL_i-311eX29CsIOo7i</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68527035</pqid></control><display><type>article</type><title>Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Maghami, Ellie G. ; Talbot, Simon G. ; Patel, Snehal G. ; Singh, Bhuvanesh ; Polluri, Ashok ; Bridger, Patrick G. ; Cantu, Giulio ; Cheesman, Anthony D. ; Sa, Geraldo De ; Donald, Paul ; dos Santos, Luiz R. M. ; Fliss, Dan ; Gullane, Patrick ; Janecka, Ivo ; Kamata, Shin‐Etsu ; Kowalski, Luiz P. ; Kraus, Dennis H. ; Levine, Paul A. ; Pradhan, Sultan ; Schramm, Victor ; Snyderman, Carl ; Wei, William I. ; Shah, Jatin P. ; Wax, Mark L.</creator><creatorcontrib>Maghami, Ellie G. ; Talbot, Simon G. ; Patel, Snehal G. ; Singh, Bhuvanesh ; Polluri, Ashok ; Bridger, Patrick G. ; Cantu, Giulio ; Cheesman, Anthony D. ; Sa, Geraldo De ; Donald, Paul ; dos Santos, Luiz R. M. ; Fliss, Dan ; Gullane, Patrick ; Janecka, Ivo ; Kamata, Shin‐Etsu ; Kowalski, Luiz P. ; Kraus, Dennis H. ; Levine, Paul A. ; Pradhan, Sultan ; Schramm, Victor ; Snyderman, Carl ; Wei, William I. ; Shah, Jatin P. ; Wax, Mark L.</creatorcontrib><description>Background.
This study examined the efficacy of craniofacial surgery (CFS) in treating locally advanced nonmelanoma skin cancer (NMSC).
Methods.
One hundred twenty patients who underwent CFS for NMSC were identified from 17 participating institutions. Patient, tumor, and treatment information was analyzed for prognostic impact on survival.
Results.
Surgical margins were negative in 74%, close in 3%, and involved in 23% of patients. Complications occurred in 35% of patients, half of which were local wound problems. Operative mortality was 4%. Median follow‐up interval after CFS was 27 months. The 5‐year overall survival (OS), disease‐specific survival (DSS), and recurrence‐free survival (RFS) rates were 64%, 75%, and 60%, respectively. Squamous cell histology, brain invasion, and positive resection margins independently predicted worse OS, DSS, and RFS.
Conclusion.
CFS is an effective treatment for patients with NMSC invading the skull base. Histology, extent of disease, and resection margins are the most significant predictors of outcome. © 2007 Wiley Periodicals, Inc. Head Neck, 2007</description><identifier>ISSN: 1043-3074</identifier><identifier>EISSN: 1097-0347</identifier><identifier>DOI: 10.1002/hed.20656</identifier><identifier>PMID: 17764086</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; basal cell carcinoma ; Biological and medical sciences ; Brain Neoplasms - mortality ; Brain Neoplasms - secondary ; Brain Neoplasms - surgery ; Carcinoma, Basal Cell - mortality ; Carcinoma, Basal Cell - pathology ; Carcinoma, Basal Cell - surgery ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - surgery ; Chemotherapy, Adjuvant ; Child ; Child, Preschool ; Dermatology ; Disease-Free Survival ; Female ; Follow-Up Studies ; head and neck ; Humans ; international collaboration ; International Cooperation ; Male ; Medical sciences ; Middle Aged ; Neoplasm Invasiveness ; Otorhinolaryngology. Stomatology ; Postoperative Complications ; Radiotherapy, Adjuvant ; skin cancer ; Skin Neoplasms - mortality ; Skin Neoplasms - pathology ; Skin Neoplasms - surgery ; skull base neoplasm ; skull base/craniofacial surgery ; Skull Neoplasms - mortality ; Skull Neoplasms - secondary ; Skull Neoplasms - surgery ; squamous cell carcinoma ; Surgical Flaps ; treatment outcome ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Head & neck, 2007-12, Vol.29 (12), p.1136-1143</ispartof><rights>Copyright © 2007 Wiley Periodicals, Inc.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3886-71f55791d1bca07eab0c5eeba65d14a35bc13a695b7111a6bcea925ba15888e03</citedby><cites>FETCH-LOGICAL-c3886-71f55791d1bca07eab0c5eeba65d14a35bc13a695b7111a6bcea925ba15888e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fhed.20656$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fhed.20656$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19866537$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17764086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maghami, Ellie G.</creatorcontrib><creatorcontrib>Talbot, Simon G.</creatorcontrib><creatorcontrib>Patel, Snehal G.</creatorcontrib><creatorcontrib>Singh, Bhuvanesh</creatorcontrib><creatorcontrib>Polluri, Ashok</creatorcontrib><creatorcontrib>Bridger, Patrick G.</creatorcontrib><creatorcontrib>Cantu, Giulio</creatorcontrib><creatorcontrib>Cheesman, Anthony D.</creatorcontrib><creatorcontrib>Sa, Geraldo De</creatorcontrib><creatorcontrib>Donald, Paul</creatorcontrib><creatorcontrib>dos Santos, Luiz R. M.</creatorcontrib><creatorcontrib>Fliss, Dan</creatorcontrib><creatorcontrib>Gullane, Patrick</creatorcontrib><creatorcontrib>Janecka, Ivo</creatorcontrib><creatorcontrib>Kamata, Shin‐Etsu</creatorcontrib><creatorcontrib>Kowalski, Luiz P.</creatorcontrib><creatorcontrib>Kraus, Dennis H.</creatorcontrib><creatorcontrib>Levine, Paul A.</creatorcontrib><creatorcontrib>Pradhan, Sultan</creatorcontrib><creatorcontrib>Schramm, Victor</creatorcontrib><creatorcontrib>Snyderman, Carl</creatorcontrib><creatorcontrib>Wei, William I.</creatorcontrib><creatorcontrib>Shah, Jatin P.</creatorcontrib><creatorcontrib>Wax, Mark L.</creatorcontrib><title>Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study</title><title>Head & neck</title><addtitle>Head Neck</addtitle><description>Background.
This study examined the efficacy of craniofacial surgery (CFS) in treating locally advanced nonmelanoma skin cancer (NMSC).
Methods.
One hundred twenty patients who underwent CFS for NMSC were identified from 17 participating institutions. Patient, tumor, and treatment information was analyzed for prognostic impact on survival.
Results.
Surgical margins were negative in 74%, close in 3%, and involved in 23% of patients. Complications occurred in 35% of patients, half of which were local wound problems. Operative mortality was 4%. Median follow‐up interval after CFS was 27 months. The 5‐year overall survival (OS), disease‐specific survival (DSS), and recurrence‐free survival (RFS) rates were 64%, 75%, and 60%, respectively. Squamous cell histology, brain invasion, and positive resection margins independently predicted worse OS, DSS, and RFS.
Conclusion.
CFS is an effective treatment for patients with NMSC invading the skull base. Histology, extent of disease, and resection margins are the most significant predictors of outcome. © 2007 Wiley Periodicals, Inc. Head Neck, 2007</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>basal cell carcinoma</subject><subject>Biological and medical sciences</subject><subject>Brain Neoplasms - mortality</subject><subject>Brain Neoplasms - secondary</subject><subject>Brain Neoplasms - surgery</subject><subject>Carcinoma, Basal Cell - mortality</subject><subject>Carcinoma, Basal Cell - pathology</subject><subject>Carcinoma, Basal Cell - surgery</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Chemotherapy, Adjuvant</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Dermatology</subject><subject>Disease-Free Survival</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>head and neck</subject><subject>Humans</subject><subject>international collaboration</subject><subject>International Cooperation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Invasiveness</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Postoperative Complications</subject><subject>Radiotherapy, Adjuvant</subject><subject>skin cancer</subject><subject>Skin Neoplasms - mortality</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - surgery</subject><subject>skull base neoplasm</subject><subject>skull base/craniofacial surgery</subject><subject>Skull Neoplasms - mortality</subject><subject>Skull Neoplasms - secondary</subject><subject>Skull Neoplasms - surgery</subject><subject>squamous cell carcinoma</subject><subject>Surgical Flaps</subject><subject>treatment outcome</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>1043-3074</issn><issn>1097-0347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1P3DAQhq0KVGDbQ_8A8oVKHAJ2HNtJb2ihBQkJCdFzNHYm1JDYWzspyr_HdFf01NN86NE7o4eQL5ydccbK81_YnZVMSfWBHHLW6IKJSu-99ZUoBNPVATlK6YkxJlRVfiQHXGtVsVodkm4dwbvQg3Uw0DTHR4wL7UOkPvgRB_BhBJqenacjDO7Rg7fLN3qPmxAnGnoKnjo_YfQwueBzhg3DACbEPP9Bmqa5Wz6R_R6GhJ93dUV-fr96WF8Xt3c_btYXt4UVda0KzXspdcM7biwwjWCYlYgGlOx4BUIaywWoRhrNOQdlLEJTSgNc1nWNTKzI123uJobfM6apHV2ymP_xGObUqlqWmgmZwdMtaGNIKWLfbqIbIS4tZ-2b0jYrbf8qzezxLnQ2Y96-kzuHGTjZAZAsDH0Wal36xzW1UlLozJ1vuRc34PL_i-311eX29CsIOo7i</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Maghami, Ellie G.</creator><creator>Talbot, Simon G.</creator><creator>Patel, Snehal G.</creator><creator>Singh, Bhuvanesh</creator><creator>Polluri, Ashok</creator><creator>Bridger, Patrick G.</creator><creator>Cantu, Giulio</creator><creator>Cheesman, Anthony D.</creator><creator>Sa, Geraldo De</creator><creator>Donald, Paul</creator><creator>dos Santos, Luiz R. M.</creator><creator>Fliss, Dan</creator><creator>Gullane, Patrick</creator><creator>Janecka, Ivo</creator><creator>Kamata, Shin‐Etsu</creator><creator>Kowalski, Luiz P.</creator><creator>Kraus, Dennis H.</creator><creator>Levine, Paul A.</creator><creator>Pradhan, Sultan</creator><creator>Schramm, Victor</creator><creator>Snyderman, Carl</creator><creator>Wei, William I.</creator><creator>Shah, Jatin P.</creator><creator>Wax, Mark L.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>John Wiley & Sons</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200712</creationdate><title>Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study</title><author>Maghami, Ellie G. ; Talbot, Simon G. ; Patel, Snehal G. ; Singh, Bhuvanesh ; Polluri, Ashok ; Bridger, Patrick G. ; Cantu, Giulio ; Cheesman, Anthony D. ; Sa, Geraldo De ; Donald, Paul ; dos Santos, Luiz R. M. ; Fliss, Dan ; Gullane, Patrick ; Janecka, Ivo ; Kamata, Shin‐Etsu ; Kowalski, Luiz P. ; Kraus, Dennis H. ; Levine, Paul A. ; Pradhan, Sultan ; Schramm, Victor ; Snyderman, Carl ; Wei, William I. ; Shah, Jatin P. ; Wax, Mark L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3886-71f55791d1bca07eab0c5eeba65d14a35bc13a695b7111a6bcea925ba15888e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>basal cell carcinoma</topic><topic>Biological and medical sciences</topic><topic>Brain Neoplasms - mortality</topic><topic>Brain Neoplasms - secondary</topic><topic>Brain Neoplasms - surgery</topic><topic>Carcinoma, Basal Cell - mortality</topic><topic>Carcinoma, Basal Cell - pathology</topic><topic>Carcinoma, Basal Cell - surgery</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Chemotherapy, Adjuvant</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Dermatology</topic><topic>Disease-Free Survival</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>head and neck</topic><topic>Humans</topic><topic>international collaboration</topic><topic>International Cooperation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Invasiveness</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Postoperative Complications</topic><topic>Radiotherapy, Adjuvant</topic><topic>skin cancer</topic><topic>Skin Neoplasms - mortality</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - surgery</topic><topic>skull base neoplasm</topic><topic>skull base/craniofacial surgery</topic><topic>Skull Neoplasms - mortality</topic><topic>Skull Neoplasms - secondary</topic><topic>Skull Neoplasms - surgery</topic><topic>squamous cell carcinoma</topic><topic>Surgical Flaps</topic><topic>treatment outcome</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maghami, Ellie G.</creatorcontrib><creatorcontrib>Talbot, Simon G.</creatorcontrib><creatorcontrib>Patel, Snehal G.</creatorcontrib><creatorcontrib>Singh, Bhuvanesh</creatorcontrib><creatorcontrib>Polluri, Ashok</creatorcontrib><creatorcontrib>Bridger, Patrick G.</creatorcontrib><creatorcontrib>Cantu, Giulio</creatorcontrib><creatorcontrib>Cheesman, Anthony D.</creatorcontrib><creatorcontrib>Sa, Geraldo De</creatorcontrib><creatorcontrib>Donald, Paul</creatorcontrib><creatorcontrib>dos Santos, Luiz R. M.</creatorcontrib><creatorcontrib>Fliss, Dan</creatorcontrib><creatorcontrib>Gullane, Patrick</creatorcontrib><creatorcontrib>Janecka, Ivo</creatorcontrib><creatorcontrib>Kamata, Shin‐Etsu</creatorcontrib><creatorcontrib>Kowalski, Luiz P.</creatorcontrib><creatorcontrib>Kraus, Dennis H.</creatorcontrib><creatorcontrib>Levine, Paul A.</creatorcontrib><creatorcontrib>Pradhan, Sultan</creatorcontrib><creatorcontrib>Schramm, Victor</creatorcontrib><creatorcontrib>Snyderman, Carl</creatorcontrib><creatorcontrib>Wei, William I.</creatorcontrib><creatorcontrib>Shah, Jatin P.</creatorcontrib><creatorcontrib>Wax, Mark L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Head & neck</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maghami, Ellie G.</au><au>Talbot, Simon G.</au><au>Patel, Snehal G.</au><au>Singh, Bhuvanesh</au><au>Polluri, Ashok</au><au>Bridger, Patrick G.</au><au>Cantu, Giulio</au><au>Cheesman, Anthony D.</au><au>Sa, Geraldo De</au><au>Donald, Paul</au><au>dos Santos, Luiz R. M.</au><au>Fliss, Dan</au><au>Gullane, Patrick</au><au>Janecka, Ivo</au><au>Kamata, Shin‐Etsu</au><au>Kowalski, Luiz P.</au><au>Kraus, Dennis H.</au><au>Levine, Paul A.</au><au>Pradhan, Sultan</au><au>Schramm, Victor</au><au>Snyderman, Carl</au><au>Wei, William I.</au><au>Shah, Jatin P.</au><au>Wax, Mark L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study</atitle><jtitle>Head & neck</jtitle><addtitle>Head Neck</addtitle><date>2007-12</date><risdate>2007</risdate><volume>29</volume><issue>12</issue><spage>1136</spage><epage>1143</epage><pages>1136-1143</pages><issn>1043-3074</issn><eissn>1097-0347</eissn><abstract>Background.
This study examined the efficacy of craniofacial surgery (CFS) in treating locally advanced nonmelanoma skin cancer (NMSC).
Methods.
One hundred twenty patients who underwent CFS for NMSC were identified from 17 participating institutions. Patient, tumor, and treatment information was analyzed for prognostic impact on survival.
Results.
Surgical margins were negative in 74%, close in 3%, and involved in 23% of patients. Complications occurred in 35% of patients, half of which were local wound problems. Operative mortality was 4%. Median follow‐up interval after CFS was 27 months. The 5‐year overall survival (OS), disease‐specific survival (DSS), and recurrence‐free survival (RFS) rates were 64%, 75%, and 60%, respectively. Squamous cell histology, brain invasion, and positive resection margins independently predicted worse OS, DSS, and RFS.
Conclusion.
CFS is an effective treatment for patients with NMSC invading the skull base. Histology, extent of disease, and resection margins are the most significant predictors of outcome. © 2007 Wiley Periodicals, Inc. Head Neck, 2007</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>17764086</pmid><doi>10.1002/hed.20656</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Head & neck, 2007-12, Vol.29 (12), p.1136-1143 |
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| subjects | Adolescent Adult Aged Aged, 80 and over basal cell carcinoma Biological and medical sciences Brain Neoplasms - mortality Brain Neoplasms - secondary Brain Neoplasms - surgery Carcinoma, Basal Cell - mortality Carcinoma, Basal Cell - pathology Carcinoma, Basal Cell - surgery Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Chemotherapy, Adjuvant Child Child, Preschool Dermatology Disease-Free Survival Female Follow-Up Studies head and neck Humans international collaboration International Cooperation Male Medical sciences Middle Aged Neoplasm Invasiveness Otorhinolaryngology. Stomatology Postoperative Complications Radiotherapy, Adjuvant skin cancer Skin Neoplasms - mortality Skin Neoplasms - pathology Skin Neoplasms - surgery skull base neoplasm skull base/craniofacial surgery Skull Neoplasms - mortality Skull Neoplasms - secondary Skull Neoplasms - surgery squamous cell carcinoma Surgical Flaps treatment outcome Tumors of the skin and soft tissue. Premalignant lesions |
| title | Craniofacial surgery for nonmelanoma skin malignancy: Report of an international collaborative study |
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