Functional characterization of NF-kappaB inhibitor-like protein 1 (NFkappaBIL1), a candidate susceptibility gene for rheumatoid arthritis

Several studies have implicated the NF-kappaB inhibitor-like protein 1 (NFkBIL1) gene located in the class III region of the major histocompatibility complex (MHC) as a possible susceptibility locus for rheumatoid arthritis (RA). Based on limited homology, it has been suggested to be a member of the...

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Veröffentlicht in:	Human molecular genetics 2007-12, Vol.16 (24), p.3027-3036
Hauptverfasser:	Greetham, Darren, Ellis, Charles D, Mewar, Devesh, Fearon, Ursula, an Ultaigh, Sinead Nic, Veale, Douglas J, Guesdon, François, Wilson, Anthony G
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - pathology Biopsy Carbon-Nitrogen Ligases - metabolism Cells, Cultured DEAD-box RNA Helicases - metabolism Female Genetic Predisposition to Disease HeLa Cells Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - metabolism Histocompatibility Antigens Class II - physiology Humans Male Neoplasm Proteins - metabolism Peptide Elongation Factor 1 - metabolism Protein Biosynthesis - genetics Protein Isoforms - metabolism RNA Processing, Post-Transcriptional RNA, Messenger - metabolism Synovial Membrane - metabolism Synovial Membrane - pathology Tissue Distribution
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