Friedolanostanes and Lanostanes from the Leaves of Garcinia hombroniana
Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G−I, 2−4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2005-08, Vol.68 (8), p.1222-1225 |
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creator | Rukachaisirikul, Vatcharin Saelim, Somsak Karnsomchoke, Pueksa Phongpaichit, Souwalak |
description | Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G−I, 2−4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-derived glycosides, and two flavonoid glucosides. Their structures were identified by analysis of spectroscopic data and comparison of the NMR data with those previously reported. |
doi_str_mv | 10.1021/np050131j |
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Their structures were identified by analysis of spectroscopic data and comparison of the NMR data with those previously reported.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np050131j</identifier><identifier>PMID: 16124765</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>antibacterial properties ; Biological and medical sciences ; chemical structure ; Flavonoids - chemistry ; Flavonoids - isolation & purification ; Flavonoids - pharmacology ; friedolanostanes ; garcihombronane ; Garcinia ; Garcinia - chemistry ; Garcinia hombroniana ; General pharmacology ; Glucosides - chemistry ; Glucosides - isolation & purification ; Glucosides - pharmacology ; lanostanes ; Lanosterol - analogs & derivatives ; Lanosterol - chemistry ; Lanosterol - isolation & purification ; Lanosterol - pharmacology ; Medical sciences ; Methicillin Resistance ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; phytochemicals ; plant biochemistry ; plant extracts ; Plant Leaves - chemistry ; Plants, Medicinal - chemistry ; spectral analysis ; Staphylococcus aureus ; Staphylococcus aureus - drug effects ; stereochemistry ; Thailand ; Triterpenes - chemistry ; Triterpenes - isolation & purification ; Triterpenes - pharmacology ; triterpenoids</subject><ispartof>Journal of natural products (Washington, D.C.), 2005-08, Vol.68 (8), p.1222-1225</ispartof><rights>Copyright © 2005 American Chemical Society and American Society of Pharmacognosy</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a405t-ee599a31df8a3f91ec38ff12a937d6353076b5946e2fa190e023ff58725036343</citedby><cites>FETCH-LOGICAL-a405t-ee599a31df8a3f91ec38ff12a937d6353076b5946e2fa190e023ff58725036343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/np050131j$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/np050131j$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2751,27055,27903,27904,56717,56767</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17059724$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16124765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rukachaisirikul, Vatcharin</creatorcontrib><creatorcontrib>Saelim, Somsak</creatorcontrib><creatorcontrib>Karnsomchoke, Pueksa</creatorcontrib><creatorcontrib>Phongpaichit, Souwalak</creatorcontrib><title>Friedolanostanes and Lanostanes from the Leaves of Garcinia hombroniana</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G−I, 2−4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-derived glycosides, and two flavonoid glucosides. Their structures were identified by analysis of spectroscopic data and comparison of the NMR data with those previously reported.</description><subject>antibacterial properties</subject><subject>Biological and medical sciences</subject><subject>chemical structure</subject><subject>Flavonoids - chemistry</subject><subject>Flavonoids - isolation & purification</subject><subject>Flavonoids - pharmacology</subject><subject>friedolanostanes</subject><subject>garcihombronane</subject><subject>Garcinia</subject><subject>Garcinia - chemistry</subject><subject>Garcinia hombroniana</subject><subject>General pharmacology</subject><subject>Glucosides - chemistry</subject><subject>Glucosides - isolation & purification</subject><subject>Glucosides - pharmacology</subject><subject>lanostanes</subject><subject>Lanosterol - analogs & derivatives</subject><subject>Lanosterol - chemistry</subject><subject>Lanosterol - isolation & purification</subject><subject>Lanosterol - pharmacology</subject><subject>Medical sciences</subject><subject>Methicillin Resistance</subject><subject>Molecular Structure</subject><subject>Nuclear Magnetic Resonance, Biomolecular</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>phytochemicals</subject><subject>plant biochemistry</subject><subject>plant extracts</subject><subject>Plant Leaves - chemistry</subject><subject>Plants, Medicinal - chemistry</subject><subject>spectral analysis</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus aureus - drug effects</subject><subject>stereochemistry</subject><subject>Thailand</subject><subject>Triterpenes - chemistry</subject><subject>Triterpenes - isolation & purification</subject><subject>Triterpenes - pharmacology</subject><subject>triterpenoids</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0MFOGzEQBmCrKiqB9tAXaPcCEoelY8_auz6WCAJSJCIlqEdrsmuXTbPr1N4geHuMEpELJ3vkT-OZn7HvHC45CP6r34AEjnz1iY24FJArEPIzGwFXmGOlimN2EuMKABC0_MKOueKiKJUcsclNaG3j19T7OFBvY0Z9k00PpQu-y4ZHm00tPaXau2xCoW77lrJH3y2DT7eevrIjR-tov-3PU_Zwc70Y3-bT-8nd-Pc0pwLkkFsrtSbkjasInea2xso5Lkhj2SiUCKVaSl0oKxxxDRYEOierUkhAhQWesvNd303w_7c2DqZrY23XaQHrt9GoSgqlVZXgxQ7WwccYrDOb0HYUXgwH85aaeU8t2R_7pttlZ5uD3MeUwNkeUKxp7QL1dRsPrgSpS_E2Xb5zbRzs8_s7hX9GlVhKs5jNDcwm4z8VXplF8j933pE39Dekng9zkYYCDoiVLg4_Ux3Nym9Dn9L9YIVXjZaXUA</recordid><startdate>20050801</startdate><enddate>20050801</enddate><creator>Rukachaisirikul, Vatcharin</creator><creator>Saelim, Somsak</creator><creator>Karnsomchoke, Pueksa</creator><creator>Phongpaichit, Souwalak</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050801</creationdate><title>Friedolanostanes and Lanostanes from the Leaves of Garcinia hombroniana</title><author>Rukachaisirikul, Vatcharin ; Saelim, Somsak ; Karnsomchoke, Pueksa ; Phongpaichit, Souwalak</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a405t-ee599a31df8a3f91ec38ff12a937d6353076b5946e2fa190e023ff58725036343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>antibacterial properties</topic><topic>Biological and medical sciences</topic><topic>chemical structure</topic><topic>Flavonoids - chemistry</topic><topic>Flavonoids - isolation & purification</topic><topic>Flavonoids - pharmacology</topic><topic>friedolanostanes</topic><topic>garcihombronane</topic><topic>Garcinia</topic><topic>Garcinia - chemistry</topic><topic>Garcinia hombroniana</topic><topic>General pharmacology</topic><topic>Glucosides - chemistry</topic><topic>Glucosides - isolation & purification</topic><topic>Glucosides - pharmacology</topic><topic>lanostanes</topic><topic>Lanosterol - analogs & derivatives</topic><topic>Lanosterol - chemistry</topic><topic>Lanosterol - isolation & purification</topic><topic>Lanosterol - pharmacology</topic><topic>Medical sciences</topic><topic>Methicillin Resistance</topic><topic>Molecular Structure</topic><topic>Nuclear Magnetic Resonance, Biomolecular</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>phytochemicals</topic><topic>plant biochemistry</topic><topic>plant extracts</topic><topic>Plant Leaves - chemistry</topic><topic>Plants, Medicinal - chemistry</topic><topic>spectral analysis</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus aureus - drug effects</topic><topic>stereochemistry</topic><topic>Thailand</topic><topic>Triterpenes - chemistry</topic><topic>Triterpenes - isolation & purification</topic><topic>Triterpenes - pharmacology</topic><topic>triterpenoids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rukachaisirikul, Vatcharin</creatorcontrib><creatorcontrib>Saelim, Somsak</creatorcontrib><creatorcontrib>Karnsomchoke, Pueksa</creatorcontrib><creatorcontrib>Phongpaichit, Souwalak</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rukachaisirikul, Vatcharin</au><au>Saelim, Somsak</au><au>Karnsomchoke, Pueksa</au><au>Phongpaichit, Souwalak</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Friedolanostanes and Lanostanes from the Leaves of Garcinia hombroniana</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2005-08-01</date><risdate>2005</risdate><volume>68</volume><issue>8</issue><spage>1222</spage><epage>1225</epage><pages>1222-1225</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G−I, 2−4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-derived glycosides, and two flavonoid glucosides. Their structures were identified by analysis of spectroscopic data and comparison of the NMR data with those previously reported.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>16124765</pmid><doi>10.1021/np050131j</doi><tpages>4</tpages></addata></record> |
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subjects | antibacterial properties Biological and medical sciences chemical structure Flavonoids - chemistry Flavonoids - isolation & purification Flavonoids - pharmacology friedolanostanes garcihombronane Garcinia Garcinia - chemistry Garcinia hombroniana General pharmacology Glucosides - chemistry Glucosides - isolation & purification Glucosides - pharmacology lanostanes Lanosterol - analogs & derivatives Lanosterol - chemistry Lanosterol - isolation & purification Lanosterol - pharmacology Medical sciences Methicillin Resistance Molecular Structure Nuclear Magnetic Resonance, Biomolecular Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phytochemicals plant biochemistry plant extracts Plant Leaves - chemistry Plants, Medicinal - chemistry spectral analysis Staphylococcus aureus Staphylococcus aureus - drug effects stereochemistry Thailand Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - pharmacology triterpenoids |
title | Friedolanostanes and Lanostanes from the Leaves of Garcinia hombroniana |
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