Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics without compromising virulence

Objectives To determine if one passage of Salmonella enterica serovar Typhimurium in the presence of farm disinfectants selected for mutants with decreased susceptibility to disinfectants and/or antibiotics. Methods Eight Salmonella Typhimurium strains including field isolates and laboratory mutants...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2007-12, Vol.60 (6), p.1273-1280
Hauptverfasser:	Randall, L. P., Cooles, S. W., Coldham, N. G., Penuela, E. G., Mott, A. C., Woodward, M. J., Piddock, L. J. V., Webber, M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animals Anti-Bacterial Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Proteins - genetics Bacterial Proteins - metabolism biocide resistance Biological and medical sciences Biomedical research Chickens - microbiology Disinfectants - pharmacology Disinfection & disinfectants Drug resistance Drug Resistance, Multiple, Bacterial - drug effects Drug Resistance, Multiple, Bacterial - genetics efflux Gene Expression Regulation, Bacterial MAR Medical sciences Microbial Sensitivity Tests Microbiology Mutation Pharmacology. Drug treatments Proteomics Salmonella Salmonella enterica Salmonella typhimurium Salmonella typhimurium - drug effects Salmonella typhimurium - genetics Salmonella typhimurium - growth & development Salmonella typhimurium - pathogenicity Selection, Genetic Virulence
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