Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction
Abstract Aims False negative cases in the intraoperative assessment of sentinel node (SN) metastases in breast cancer prompt for a secondary axillary lymph node dissection (ALND). Such ALND is technically demanding and prone to complications in patients with immediate breast reconstruction (IBR) if...
Gespeichert in:
| Veröffentlicht in: | European journal of surgical oncology 2007-12, Vol.33 (10), p.1146-1149 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1149 |
|---|---|
| container_issue | 10 |
| container_start_page | 1146 |
| container_title | European journal of surgical oncology |
| container_volume | 33 |
| creator | Meretoja, T.J Jahkola, T.A Toivonen, T.S Krogerus, L.A Heikkilä, P.S von Smitten, K.A.J Leidenius, M.H.K |
| description | Abstract Aims False negative cases in the intraoperative assessment of sentinel node (SN) metastases in breast cancer prompt for a secondary axillary lymph node dissection (ALND). Such ALND is technically demanding and prone to complications in patients with immediate breast reconstruction (IBR) if there is a microvascular anastomosis or the thoracodorsal pedicle of a latissimus dorsi flap in the axilla. This study aims to evaluate the feasibility of the intraoperative diagnosis of sentinel node biopsy (SNB) in breast cancer patients undergoing IBR. Methods Sixty-two consecutive breast cancer patients undergoing SNB with the intraoperative diagnosis of SN metastases simultaneously with mastectomy and IBR between 2004 and 2006 were included in this study. Results of the SNB and especially the false negative cases in the intraoperative diagnosis were evaluated. Results Eleven patients had tumor positive SN. Nine of these cases were detected intraoperatively. The two false negative cases in the intraoperative diagnosis constituted of isolated tumor cells only. Conclusions Our present study suggests that SNB with intraoperative diagnosis of SN metastases is feasible in patients undergoing IBR if the risk of nodal metastasis is low and the sensitivity of intraoperative SNB diagnosis is high. |
| doi_str_mv | 10.1016/j.ejso.2007.03.009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68526524</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0748798307001357</els_id><sourcerecordid>68526524</sourcerecordid><originalsourceid>FETCH-LOGICAL-c409t-f1425cbb8475d0a0f398f4984b0493d1a3316f7eadad4a9619cddb76e83e52ec3</originalsourceid><addsrcrecordid>eNp9kc-KFDEQxoMo7uzoC3iQnLx1m3_d6QYRZFFXWPCweg7ppHrMbHfSJumVeQDf2zQzIHjwFCr1fV9Rv0LoFSU1JbR9e6zhmELNCJE14TUh_RO0ow1nFaONfIp2RIqukn3Hr9B1SkdSFFz2z9EVlaJlXUN36Pc9-Ow8TNgHC3hwYUkn_MvlH9j5HHVYIOrsHgFbpw8-JJdKAy_lrxgTXr2FeAjOH3B6cL5Ki45bMeuUweQwn7D2Frt5hhKQy4QIpYUjmOBTjqvJLvgX6NmopwQvL-8eff_08dvNbXX39fOXmw93lRGkz9VIBWvMMHRCNpZoMvK-G0XfiYGInluqOaftKEFbbYXuW9obawfZQsehYWD4Hr055y4x_FwhZTW7ZGCatIewJtV2DWsbJoqQnYUmhpQijGqJbtbxpChRG3x1VBt8tcFXhKsN7R69vqSvQ1n3r-VCuwjenQVQdnx0EFUyBaMpaAqPrGxw_89__4_dTM47o6cHOEE6hjX6Qk9RlZgi6n47_3Z9IgmhvJH8DyY6r2k</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68526524</pqid></control><display><type>article</type><title>Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Meretoja, T.J ; Jahkola, T.A ; Toivonen, T.S ; Krogerus, L.A ; Heikkilä, P.S ; von Smitten, K.A.J ; Leidenius, M.H.K</creator><creatorcontrib>Meretoja, T.J ; Jahkola, T.A ; Toivonen, T.S ; Krogerus, L.A ; Heikkilä, P.S ; von Smitten, K.A.J ; Leidenius, M.H.K</creatorcontrib><description>Abstract Aims False negative cases in the intraoperative assessment of sentinel node (SN) metastases in breast cancer prompt for a secondary axillary lymph node dissection (ALND). Such ALND is technically demanding and prone to complications in patients with immediate breast reconstruction (IBR) if there is a microvascular anastomosis or the thoracodorsal pedicle of a latissimus dorsi flap in the axilla. This study aims to evaluate the feasibility of the intraoperative diagnosis of sentinel node biopsy (SNB) in breast cancer patients undergoing IBR. Methods Sixty-two consecutive breast cancer patients undergoing SNB with the intraoperative diagnosis of SN metastases simultaneously with mastectomy and IBR between 2004 and 2006 were included in this study. Results of the SNB and especially the false negative cases in the intraoperative diagnosis were evaluated. Results Eleven patients had tumor positive SN. Nine of these cases were detected intraoperatively. The two false negative cases in the intraoperative diagnosis constituted of isolated tumor cells only. Conclusions Our present study suggests that SNB with intraoperative diagnosis of SN metastases is feasible in patients undergoing IBR if the risk of nodal metastasis is low and the sensitivity of intraoperative SNB diagnosis is high.</description><identifier>ISSN: 0748-7983</identifier><identifier>EISSN: 1532-2157</identifier><identifier>DOI: 10.1016/j.ejso.2007.03.009</identifier><identifier>PMID: 17462851</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Aged ; Axilla ; Breast cancer ; Breast Neoplasms - pathology ; Breast Neoplasms - surgery ; False Negative Reactions ; Feasibility Studies ; Female ; Hematology, Oncology and Palliative Medicine ; Humans ; Immediate breast reconstruction ; Intraoperative Period ; Lymph Node Excision ; Lymphatic Metastasis ; Mammaplasty ; Mastectomy ; Middle Aged ; Neoplasm Staging ; Sensitivity and Specificity ; Sentinel Lymph Node Biopsy ; Sentinel node biopsy ; Skin-sparing mastectomy ; Surgery</subject><ispartof>European journal of surgical oncology, 2007-12, Vol.33 (10), p.1146-1149</ispartof><rights>Elsevier Ltd</rights><rights>2007 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-f1425cbb8475d0a0f398f4984b0493d1a3316f7eadad4a9619cddb76e83e52ec3</citedby><cites>FETCH-LOGICAL-c409t-f1425cbb8475d0a0f398f4984b0493d1a3316f7eadad4a9619cddb76e83e52ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0748798307001357$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17462851$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Meretoja, T.J</creatorcontrib><creatorcontrib>Jahkola, T.A</creatorcontrib><creatorcontrib>Toivonen, T.S</creatorcontrib><creatorcontrib>Krogerus, L.A</creatorcontrib><creatorcontrib>Heikkilä, P.S</creatorcontrib><creatorcontrib>von Smitten, K.A.J</creatorcontrib><creatorcontrib>Leidenius, M.H.K</creatorcontrib><title>Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction</title><title>European journal of surgical oncology</title><addtitle>Eur J Surg Oncol</addtitle><description>Abstract Aims False negative cases in the intraoperative assessment of sentinel node (SN) metastases in breast cancer prompt for a secondary axillary lymph node dissection (ALND). Such ALND is technically demanding and prone to complications in patients with immediate breast reconstruction (IBR) if there is a microvascular anastomosis or the thoracodorsal pedicle of a latissimus dorsi flap in the axilla. This study aims to evaluate the feasibility of the intraoperative diagnosis of sentinel node biopsy (SNB) in breast cancer patients undergoing IBR. Methods Sixty-two consecutive breast cancer patients undergoing SNB with the intraoperative diagnosis of SN metastases simultaneously with mastectomy and IBR between 2004 and 2006 were included in this study. Results of the SNB and especially the false negative cases in the intraoperative diagnosis were evaluated. Results Eleven patients had tumor positive SN. Nine of these cases were detected intraoperatively. The two false negative cases in the intraoperative diagnosis constituted of isolated tumor cells only. Conclusions Our present study suggests that SNB with intraoperative diagnosis of SN metastases is feasible in patients undergoing IBR if the risk of nodal metastasis is low and the sensitivity of intraoperative SNB diagnosis is high.</description><subject>Adult</subject><subject>Aged</subject><subject>Axilla</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - surgery</subject><subject>False Negative Reactions</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Immediate breast reconstruction</subject><subject>Intraoperative Period</subject><subject>Lymph Node Excision</subject><subject>Lymphatic Metastasis</subject><subject>Mammaplasty</subject><subject>Mastectomy</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Sensitivity and Specificity</subject><subject>Sentinel Lymph Node Biopsy</subject><subject>Sentinel node biopsy</subject><subject>Skin-sparing mastectomy</subject><subject>Surgery</subject><issn>0748-7983</issn><issn>1532-2157</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc-KFDEQxoMo7uzoC3iQnLx1m3_d6QYRZFFXWPCweg7ppHrMbHfSJumVeQDf2zQzIHjwFCr1fV9Rv0LoFSU1JbR9e6zhmELNCJE14TUh_RO0ow1nFaONfIp2RIqukn3Hr9B1SkdSFFz2z9EVlaJlXUN36Pc9-Ow8TNgHC3hwYUkn_MvlH9j5HHVYIOrsHgFbpw8-JJdKAy_lrxgTXr2FeAjOH3B6cL5Ki45bMeuUweQwn7D2Frt5hhKQy4QIpYUjmOBTjqvJLvgX6NmopwQvL-8eff_08dvNbXX39fOXmw93lRGkz9VIBWvMMHRCNpZoMvK-G0XfiYGInluqOaftKEFbbYXuW9obawfZQsehYWD4Hr055y4x_FwhZTW7ZGCatIewJtV2DWsbJoqQnYUmhpQijGqJbtbxpChRG3x1VBt8tcFXhKsN7R69vqSvQ1n3r-VCuwjenQVQdnx0EFUyBaMpaAqPrGxw_89__4_dTM47o6cHOEE6hjX6Qk9RlZgi6n47_3Z9IgmhvJH8DyY6r2k</recordid><startdate>20071201</startdate><enddate>20071201</enddate><creator>Meretoja, T.J</creator><creator>Jahkola, T.A</creator><creator>Toivonen, T.S</creator><creator>Krogerus, L.A</creator><creator>Heikkilä, P.S</creator><creator>von Smitten, K.A.J</creator><creator>Leidenius, M.H.K</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20071201</creationdate><title>Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction</title><author>Meretoja, T.J ; Jahkola, T.A ; Toivonen, T.S ; Krogerus, L.A ; Heikkilä, P.S ; von Smitten, K.A.J ; Leidenius, M.H.K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-f1425cbb8475d0a0f398f4984b0493d1a3316f7eadad4a9619cddb76e83e52ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Axilla</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - pathology</topic><topic>Breast Neoplasms - surgery</topic><topic>False Negative Reactions</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Immediate breast reconstruction</topic><topic>Intraoperative Period</topic><topic>Lymph Node Excision</topic><topic>Lymphatic Metastasis</topic><topic>Mammaplasty</topic><topic>Mastectomy</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Sensitivity and Specificity</topic><topic>Sentinel Lymph Node Biopsy</topic><topic>Sentinel node biopsy</topic><topic>Skin-sparing mastectomy</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meretoja, T.J</creatorcontrib><creatorcontrib>Jahkola, T.A</creatorcontrib><creatorcontrib>Toivonen, T.S</creatorcontrib><creatorcontrib>Krogerus, L.A</creatorcontrib><creatorcontrib>Heikkilä, P.S</creatorcontrib><creatorcontrib>von Smitten, K.A.J</creatorcontrib><creatorcontrib>Leidenius, M.H.K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meretoja, T.J</au><au>Jahkola, T.A</au><au>Toivonen, T.S</au><au>Krogerus, L.A</au><au>Heikkilä, P.S</au><au>von Smitten, K.A.J</au><au>Leidenius, M.H.K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction</atitle><jtitle>European journal of surgical oncology</jtitle><addtitle>Eur J Surg Oncol</addtitle><date>2007-12-01</date><risdate>2007</risdate><volume>33</volume><issue>10</issue><spage>1146</spage><epage>1149</epage><pages>1146-1149</pages><issn>0748-7983</issn><eissn>1532-2157</eissn><abstract>Abstract Aims False negative cases in the intraoperative assessment of sentinel node (SN) metastases in breast cancer prompt for a secondary axillary lymph node dissection (ALND). Such ALND is technically demanding and prone to complications in patients with immediate breast reconstruction (IBR) if there is a microvascular anastomosis or the thoracodorsal pedicle of a latissimus dorsi flap in the axilla. This study aims to evaluate the feasibility of the intraoperative diagnosis of sentinel node biopsy (SNB) in breast cancer patients undergoing IBR. Methods Sixty-two consecutive breast cancer patients undergoing SNB with the intraoperative diagnosis of SN metastases simultaneously with mastectomy and IBR between 2004 and 2006 were included in this study. Results of the SNB and especially the false negative cases in the intraoperative diagnosis were evaluated. Results Eleven patients had tumor positive SN. Nine of these cases were detected intraoperatively. The two false negative cases in the intraoperative diagnosis constituted of isolated tumor cells only. Conclusions Our present study suggests that SNB with intraoperative diagnosis of SN metastases is feasible in patients undergoing IBR if the risk of nodal metastasis is low and the sensitivity of intraoperative SNB diagnosis is high.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>17462851</pmid><doi>10.1016/j.ejso.2007.03.009</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0748-7983 |
| ispartof | European journal of surgical oncology, 2007-12, Vol.33 (10), p.1146-1149 |
| issn | 0748-7983 1532-2157 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68526524 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Aged Axilla Breast cancer Breast Neoplasms - pathology Breast Neoplasms - surgery False Negative Reactions Feasibility Studies Female Hematology, Oncology and Palliative Medicine Humans Immediate breast reconstruction Intraoperative Period Lymph Node Excision Lymphatic Metastasis Mammaplasty Mastectomy Middle Aged Neoplasm Staging Sensitivity and Specificity Sentinel Lymph Node Biopsy Sentinel node biopsy Skin-sparing mastectomy Surgery |
| title | Sentinel node biopsy with intraoperative diagnosis in patients undergoing skin-sparing mastectomy and immediate breast reconstruction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T09%3A52%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sentinel%20node%20biopsy%20with%20intraoperative%20diagnosis%20in%20patients%20undergoing%20skin-sparing%20mastectomy%20and%20immediate%20breast%20reconstruction&rft.jtitle=European%20journal%20of%20surgical%20oncology&rft.au=Meretoja,%20T.J&rft.date=2007-12-01&rft.volume=33&rft.issue=10&rft.spage=1146&rft.epage=1149&rft.pages=1146-1149&rft.issn=0748-7983&rft.eissn=1532-2157&rft_id=info:doi/10.1016/j.ejso.2007.03.009&rft_dat=%3Cproquest_cross%3E68526524%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68526524&rft_id=info:pmid/17462851&rft_els_id=1_s2_0_S0748798307001357&rfr_iscdi=true |