Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome
In idiopathic carpal tunnel syndrome (CTS), the median nerve is enlarged within the carpal tunnel due to intraneural connective tissue proliferation. Because hypercholesterolemia, especially increase in low‐density lipoprotein (LDL), has been associated with fibrogenesis, we investigated the associa...
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| Veröffentlicht in: | Muscle & nerve 2005-09, Vol.32 (3), p.364-367 |
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| creator | Nakamichi, Ken-Ichi Tachibana, Shintaro |
| description | In idiopathic carpal tunnel syndrome (CTS), the median nerve is enlarged within the carpal tunnel due to intraneural connective tissue proliferation. Because hypercholesterolemia, especially increase in low‐density lipoprotein (LDL), has been associated with fibrogenesis, we investigated the association of median nerve cross‐sectional area and prevalence of idiopathic CTS with serum lipid measurements in middle‐aged patients and controls. We found that nerve area and prevalence of CTS were correlated with serum LDL levels. Thus, high LDL levels in middle age are a risk factor for idiopathic CTS, suggesting that the LDL‐correlated median nerve enlargement increases the volume of the carpal tunnel contents. Muscle Nerve, 2005 |
| doi_str_mv | 10.1002/mus.20363 |
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Because hypercholesterolemia, especially increase in low‐density lipoprotein (LDL), has been associated with fibrogenesis, we investigated the association of median nerve cross‐sectional area and prevalence of idiopathic CTS with serum lipid measurements in middle‐aged patients and controls. We found that nerve area and prevalence of CTS were correlated with serum LDL levels. Thus, high LDL levels in middle age are a risk factor for idiopathic CTS, suggesting that the LDL‐correlated median nerve enlargement increases the volume of the carpal tunnel contents. Muscle Nerve, 2005</description><identifier>ISSN: 0148-639X</identifier><identifier>EISSN: 1097-4598</identifier><identifier>DOI: 10.1002/mus.20363</identifier><identifier>PMID: 15937877</identifier><identifier>CODEN: MUNEDE</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Biological and medical sciences ; carpal tunnel syndrome ; Carpal Tunnel Syndrome - diagnostic imaging ; Carpal Tunnel Syndrome - etiology ; Carpal Tunnel Syndrome - physiopathology ; cholesterol ; Cholesterol - blood ; Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction ; Cross-Sectional Studies ; Female ; Humans ; Hypercholesterolemia - blood ; Hypercholesterolemia - complications ; Hypercholesterolemia - physiopathology ; Hypertrophy - blood ; Hypertrophy - diagnostic imaging ; Hypertrophy - etiology ; Lipoproteins, LDL - blood ; low-density lipoprotein ; Male ; Median Nerve - diagnostic imaging ; Median Nerve - physiopathology ; median nerve enlargement ; Medical sciences ; Middle Aged ; Nervous system (semeiology, syndromes) ; Neurology ; Risk Factors ; Ultrasonography</subject><ispartof>Muscle & nerve, 2005-09, Vol.32 (3), p.364-367</ispartof><rights>Copyright © 2005 Wiley Periodicals, Inc.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3913-6706ab9d9b24b5e61f808c69d19f5ce14f2c7622cfabacb0d33468a8006854e3</citedby><cites>FETCH-LOGICAL-c3913-6706ab9d9b24b5e61f808c69d19f5ce14f2c7622cfabacb0d33468a8006854e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmus.20363$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmus.20363$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17062479$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15937877$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakamichi, Ken-Ichi</creatorcontrib><creatorcontrib>Tachibana, Shintaro</creatorcontrib><title>Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome</title><title>Muscle & nerve</title><addtitle>Muscle Nerve</addtitle><description>In idiopathic carpal tunnel syndrome (CTS), the median nerve is enlarged within the carpal tunnel due to intraneural connective tissue proliferation. Because hypercholesterolemia, especially increase in low‐density lipoprotein (LDL), has been associated with fibrogenesis, we investigated the association of median nerve cross‐sectional area and prevalence of idiopathic CTS with serum lipid measurements in middle‐aged patients and controls. We found that nerve area and prevalence of CTS were correlated with serum LDL levels. Thus, high LDL levels in middle age are a risk factor for idiopathic CTS, suggesting that the LDL‐correlated median nerve enlargement increases the volume of the carpal tunnel contents. Muscle Nerve, 2005</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>carpal tunnel syndrome</subject><subject>Carpal Tunnel Syndrome - diagnostic imaging</subject><subject>Carpal Tunnel Syndrome - etiology</subject><subject>Carpal Tunnel Syndrome - physiopathology</subject><subject>cholesterol</subject><subject>Cholesterol - blood</subject><subject>Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Hypercholesterolemia - blood</subject><subject>Hypercholesterolemia - complications</subject><subject>Hypercholesterolemia - physiopathology</subject><subject>Hypertrophy - blood</subject><subject>Hypertrophy - diagnostic imaging</subject><subject>Hypertrophy - etiology</subject><subject>Lipoproteins, LDL - blood</subject><subject>low-density lipoprotein</subject><subject>Male</subject><subject>Median Nerve - diagnostic imaging</subject><subject>Median Nerve - physiopathology</subject><subject>median nerve enlargement</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Risk Factors</subject><subject>Ultrasonography</subject><issn>0148-639X</issn><issn>1097-4598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10blOxDAQBmALgWA5Cl4ApQGJImDHiY8ScbMLFICgsyaOLQy5sDeCfXsMu0BFYU3zzYz9G6Ftgg8IxtlhM4SDDFNGl9CIYMnTvJBiGY0wyUXKqHxaQ-shvGCMiWB8Fa2RQlIuOB-h8cWsN14_d7UJU-NjaRwkEBJIvAuviQU97Xxi43GV63qYPjudaPA91Ml0aFtTJ2HWVr5rzCZasVAHs7WoG-j-7PT--CKd3J5fHh9NUk0loSnjmEEpK1lmeVkYRqzAQjNZEWkLbUhuM81ZlmkLJegSV5TmTIDAmIkiN3QD7c3H9r57G-K1VeOCNnUNremGoKLKCoZFhPtzqH0XgjdW9d414GeKYPUVnIrBqe_got1ZDB3KxlR_cpFUBLsLAEFDbT202oU_Fx-V5VxGdzh37642s_83quuHu5_V6bzDxR_4-O0A_6oYp7xQjzfnSl6Ni5uzk7Ga0E8DyJRd</recordid><startdate>200509</startdate><enddate>200509</enddate><creator>Nakamichi, Ken-Ichi</creator><creator>Tachibana, Shintaro</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200509</creationdate><title>Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome</title><author>Nakamichi, Ken-Ichi ; Tachibana, Shintaro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3913-6706ab9d9b24b5e61f808c69d19f5ce14f2c7622cfabacb0d33468a8006854e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>carpal tunnel syndrome</topic><topic>Carpal Tunnel Syndrome - diagnostic imaging</topic><topic>Carpal Tunnel Syndrome - etiology</topic><topic>Carpal Tunnel Syndrome - physiopathology</topic><topic>cholesterol</topic><topic>Cholesterol - blood</topic><topic>Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Hypercholesterolemia - blood</topic><topic>Hypercholesterolemia - complications</topic><topic>Hypercholesterolemia - physiopathology</topic><topic>Hypertrophy - blood</topic><topic>Hypertrophy - diagnostic imaging</topic><topic>Hypertrophy - etiology</topic><topic>Lipoproteins, LDL - blood</topic><topic>low-density lipoprotein</topic><topic>Male</topic><topic>Median Nerve - diagnostic imaging</topic><topic>Median Nerve - physiopathology</topic><topic>median nerve enlargement</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Risk Factors</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakamichi, Ken-Ichi</creatorcontrib><creatorcontrib>Tachibana, Shintaro</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Muscle & nerve</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamichi, Ken-Ichi</au><au>Tachibana, Shintaro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome</atitle><jtitle>Muscle & nerve</jtitle><addtitle>Muscle Nerve</addtitle><date>2005-09</date><risdate>2005</risdate><volume>32</volume><issue>3</issue><spage>364</spage><epage>367</epage><pages>364-367</pages><issn>0148-639X</issn><eissn>1097-4598</eissn><coden>MUNEDE</coden><abstract>In idiopathic carpal tunnel syndrome (CTS), the median nerve is enlarged within the carpal tunnel due to intraneural connective tissue proliferation. Because hypercholesterolemia, especially increase in low‐density lipoprotein (LDL), has been associated with fibrogenesis, we investigated the association of median nerve cross‐sectional area and prevalence of idiopathic CTS with serum lipid measurements in middle‐aged patients and controls. We found that nerve area and prevalence of CTS were correlated with serum LDL levels. Thus, high LDL levels in middle age are a risk factor for idiopathic CTS, suggesting that the LDL‐correlated median nerve enlargement increases the volume of the carpal tunnel contents. Muscle Nerve, 2005</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>15937877</pmid><doi>10.1002/mus.20363</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Biological and medical sciences carpal tunnel syndrome Carpal Tunnel Syndrome - diagnostic imaging Carpal Tunnel Syndrome - etiology Carpal Tunnel Syndrome - physiopathology cholesterol Cholesterol - blood Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction Cross-Sectional Studies Female Humans Hypercholesterolemia - blood Hypercholesterolemia - complications Hypercholesterolemia - physiopathology Hypertrophy - blood Hypertrophy - diagnostic imaging Hypertrophy - etiology Lipoproteins, LDL - blood low-density lipoprotein Male Median Nerve - diagnostic imaging Median Nerve - physiopathology median nerve enlargement Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Risk Factors Ultrasonography |
| title | Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome |
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