Early growth response gene 1 (EGR1) is deleted in estrogen receptor‐negative human breast carcinoma

BACKGROUND Patients with estrogen receptor (ER)‐positive and ER‐negative breast carcinomas differ in terms of disease progression, treatment regimens, and prognosis. The mechanism underlying the biologic differences of the two groups is understood poorly. Array comparative genome hybridization (CGH)...

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Veröffentlicht in:	Cancer 2005-09, Vol.104 (5), p.925-930
Hauptverfasser:	Ronski, Karyn, Sanders, Melinda, Burleson, Joseph A., Moyo, Victor, Benn, Peter, Fang, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences breast carcinoma Breast Neoplasms - chemistry Breast Neoplasms - genetics Chromosome aberrations DNA-Binding Proteins - genetics Early Growth Response Protein 1 EGR1 estrogen receptor Female Gene Deletion Genes, erbB-2 Humans Immediate-Early Proteins - genetics Loss of Heterozygosity Medical genetics Medical sciences Receptors, Estrogen - analysis Transcription Factors - genetics tumor suppressor Tumors
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