Rapid and Efficient Synthesis of 4-Substituted Pyrazol-5-one under Microwave Irradiation in Solvent-Free Conditions

New heterocyclic compounds containing pyrazol‐5‐one coupled with benzimidazole, benzothiazole, benzoxazole, quinoline, naphthyridin, and pyrazole were synthesized. Comparative investigations to synthesize these interesting classes of heterocyclic compounds through conventional heating or under micro...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2007-11, Vol.340 (11), p.591-598
Hauptverfasser:	Zahran, Magdy A.-H., El-Essawy, Farag A-A., Yassin, Salah M., Salem, Tarek A-R., Boshta, Nader M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Antitumor Benzazoles Carcinoma, Ehrlich Tumor - drug therapy Carcinoma, Ehrlich Tumor - pathology Cell Line, Tumor Cell Survival - drug effects Drug Design Drug Screening Assays, Antitumor Female Mice Microwave Microwaves Pyrazoles - chemical synthesis Pyrazoles - chemistry Pyrazoles - pharmacokinetics Pyrazoles - therapeutic use Pyrazolone Quinoline Solvents Time Factors
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