Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma
To examine whether transcatheter embolization of bone metastases is an effective palliative option for patients with renal cell carcinoma (RCCa). A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic...
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Veröffentlicht in: | Acta oncologica 2007, Vol.46 (7), p.1012-1018 |
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creator | Forauer, Andrew R. Kent, Elizabeth Cwikiel, Wojciech Esper, Peggy Redman, Bruce |
description | To examine whether transcatheter embolization of bone metastases is an effective palliative option for patients with renal cell carcinoma (RCCa). A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic sites, procedural details, and embolization materials were collected. The clinical response of the patient was assessed from clinic visits and analgesic use. Thirty separate embolization procedures were used to treat 39 metastatic lesions (18 pelvic, 8 lower extremity, 3 upper extremity, 5 rib/chest wall, and 5 vertebral lesions). Five patients underwent more than one embolization. Polyvinyl alcohol was used in all 30 embolization procedures. Additional embolic materials were used in 16 of 30 procedures. A clinical response was achieved at 36 treated sites; the mean duration of the response was 5.5 months. Selective embolization of bony renal cell carcinoma metastases can provide effective palliation in a patient population which has limited therapeutic options. |
doi_str_mv | 10.1080/02841860701280725 |
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A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic sites, procedural details, and embolization materials were collected. The clinical response of the patient was assessed from clinic visits and analgesic use. Thirty separate embolization procedures were used to treat 39 metastatic lesions (18 pelvic, 8 lower extremity, 3 upper extremity, 5 rib/chest wall, and 5 vertebral lesions). Five patients underwent more than one embolization. Polyvinyl alcohol was used in all 30 embolization procedures. Additional embolic materials were used in 16 of 30 procedures. A clinical response was achieved at 36 treated sites; the mean duration of the response was 5.5 months. 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A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic sites, procedural details, and embolization materials were collected. The clinical response of the patient was assessed from clinic visits and analgesic use. Thirty separate embolization procedures were used to treat 39 metastatic lesions (18 pelvic, 8 lower extremity, 3 upper extremity, 5 rib/chest wall, and 5 vertebral lesions). Five patients underwent more than one embolization. Polyvinyl alcohol was used in all 30 embolization procedures. Additional embolic materials were used in 16 of 30 procedures. A clinical response was achieved at 36 treated sites; the mean duration of the response was 5.5 months. Selective embolization of bony renal cell carcinoma metastases can provide effective palliation in a patient population which has limited therapeutic options.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiography</subject><subject>Bone Neoplasms - diagnostic imaging</subject><subject>Bone Neoplasms - secondary</subject><subject>Bone Neoplasms - therapy</subject><subject>Carcinoma, Renal Cell - secondary</subject><subject>Catheterization</subject><subject>Embolization, Therapeutic - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Neoplasms - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Palliative Care - methods</subject><subject>Polyvinyl Alcohol - administration & dosage</subject><subject>Retrospective Studies</subject><issn>0284-186X</issn><issn>1651-226X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRbK3-AC-Sk7fo7Ca7SfAkxS8oeFChByFMNrM0JcnW3VSov96tLXgQhGFnYZ55GR7GzjlcccjhGkSe8lxBBlzkkAl5wMZcSR4LoeaHbLydxwGYj9iJ90sAEEkmj9mIZ7nkeVqM2fsLtaSH5pOiFbZtgz_fwWHvNQ4LGshF1FW2bb7CyPaRNVFl-03U0YA-FPnIONtFjnpsI01teNDpprcdnrIjg62ns32fsLf7u9fpYzx7fnia3s5inSoYYtR1plKRaVkASsUh1TzBLMkhXCvqtEqhltxoyrQqCoV1VWkjeM21IS21SSbscpe7cvZjTX4ou8ZvT8Ge7NqXKpcCpFIB5DtQO-u9I1OuXNOh25Qcyq3S8o_SsHOxD19XHdW_G3uHAbjZAU1vrOtwQdgOiyCByqVdu6DF_xP_DVkuhcg</recordid><startdate>2007</startdate><enddate>2007</enddate><creator>Forauer, Andrew R.</creator><creator>Kent, Elizabeth</creator><creator>Cwikiel, Wojciech</creator><creator>Esper, Peggy</creator><creator>Redman, Bruce</creator><general>Informa UK Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2007</creationdate><title>Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma</title><author>Forauer, Andrew R. ; Kent, Elizabeth ; Cwikiel, Wojciech ; Esper, Peggy ; Redman, Bruce</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-acd76427c590a56104c13a73803752d4b40d51fce7c6996adbbcf21d1cfec5cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiography</topic><topic>Bone Neoplasms - diagnostic imaging</topic><topic>Bone Neoplasms - secondary</topic><topic>Bone Neoplasms - therapy</topic><topic>Carcinoma, Renal Cell - secondary</topic><topic>Catheterization</topic><topic>Embolization, Therapeutic - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney Neoplasms - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Palliative Care - methods</topic><topic>Polyvinyl Alcohol - administration & dosage</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Forauer, Andrew R.</creatorcontrib><creatorcontrib>Kent, Elizabeth</creatorcontrib><creatorcontrib>Cwikiel, Wojciech</creatorcontrib><creatorcontrib>Esper, Peggy</creatorcontrib><creatorcontrib>Redman, Bruce</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta oncologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Forauer, Andrew R.</au><au>Kent, Elizabeth</au><au>Cwikiel, Wojciech</au><au>Esper, Peggy</au><au>Redman, Bruce</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma</atitle><jtitle>Acta oncologica</jtitle><addtitle>Acta Oncol</addtitle><date>2007</date><risdate>2007</risdate><volume>46</volume><issue>7</issue><spage>1012</spage><epage>1018</epage><pages>1012-1018</pages><issn>0284-186X</issn><eissn>1651-226X</eissn><abstract>To examine whether transcatheter embolization of bone metastases is an effective palliative option for patients with renal cell carcinoma (RCCa). A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic sites, procedural details, and embolization materials were collected. The clinical response of the patient was assessed from clinic visits and analgesic use. Thirty separate embolization procedures were used to treat 39 metastatic lesions (18 pelvic, 8 lower extremity, 3 upper extremity, 5 rib/chest wall, and 5 vertebral lesions). Five patients underwent more than one embolization. Polyvinyl alcohol was used in all 30 embolization procedures. Additional embolic materials were used in 16 of 30 procedures. A clinical response was achieved at 36 treated sites; the mean duration of the response was 5.5 months. Selective embolization of bony renal cell carcinoma metastases can provide effective palliation in a patient population which has limited therapeutic options.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>17851849</pmid><doi>10.1080/02841860701280725</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Angiography Bone Neoplasms - diagnostic imaging Bone Neoplasms - secondary Bone Neoplasms - therapy Carcinoma, Renal Cell - secondary Catheterization Embolization, Therapeutic - methods Female Humans Kidney Neoplasms - pathology Male Middle Aged Palliative Care - methods Polyvinyl Alcohol - administration & dosage Retrospective Studies |
title | Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma |
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