Role of maternal corticosterone in the development and maturation of the aminoacidergic systems of the rat brain

Previous studies have suggested an important role for maternal glucocorticoids in the development of the aminoacidergic systems of the rat brain. This study examines the effect of metyrapone (2‐methyl‐1,2‐di‐3‐pyridyl‐1‐propanone), i.p.‐administered to gestating mothers, on the maturation of the ami...

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Veröffentlicht in:	International journal of developmental neuroscience 2007-11, Vol.25 (7), p.465-471
Hauptverfasser:	Leret, Maria Luisa, Lecumberri, Mar, Garcia‐Montojo, Marta, González, José Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Amino Acids - metabolism Amino Acids - physiology Animals Brain - growth & development Brain Chemistry - drug effects Brain Chemistry - physiology Chromatography, High Pressure Liquid Corticosterone Corticosterone - antagonists & inhibitors Corticosterone - physiology Development Electrochemistry Enzyme Inhibitors - pharmacology Female GABA GAD gamma-Aminobutyric Acid - metabolism Glutamate Glutamate Decarboxylase - metabolism Glutamic Acid - metabolism Male Metyrapone Metyrapone - pharmacology Pregnancy Rats Rats, Wistar Sex Characteristics
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