Oxathiaphospholane Approach to the Synthesis of Oligodeoxyribonucleotides Containing Stereodefined Internucleotide Phosphoroselenoate Function

5‘-O-DMT-deoxyribonucleoside-3‘-O-(2-selena-4,4-pentamethylene-1,3,2-oxathiaphospholane) monomers, derivatives of dA, dC, dG, and T, can be resolved into pure P-diastereomers by silica gel column chromatography. They have been used for DBU-promoted, either solution- or solid-phase synthesis of P-ste...

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Veröffentlicht in:	Organic letters 2005-09, Vol.7 (18), p.3901-3904
Hauptverfasser:	Guga, Piotr, Maciaszek, Anna, Stec, Wojciech J
Format:	Artikel
Sprache:	eng
Schlagworte:	Molecular Structure Nucleotides - chemistry Oligodeoxyribonucleotides - chemical synthesis Oligodeoxyribonucleotides - chemistry Organoselenium Compounds - chemical synthesis Organoselenium Compounds - chemistry Ribose - analogs & derivatives Ribose - chemistry Stereoisomerism
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