Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism

Accurate analysis of DNA sequence variation in not only humans and animals but also other organisms has played a significant role in expanding our knowledge about genetic variety and diversity in a number of different biological areas. The search for an understanding of the causes of genetic variant...

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Veröffentlicht in:	Nature protocols 2007-11, Vol.2 (11), p.2857-2864
Hauptverfasser:	Ota, Masao, Fukushima, Hirofumi, Kulski, Jerzy K, Inoko, Hidetoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) - genetics ABO Blood-Group System - chemistry ABO Blood-Group System - genetics Analytical Chemistry Base Sequence Biological Techniques Biomedical and Life Sciences Computational Biology/Bioinformatics Deoxyribonucleic acid DNA DNA Restriction Enzymes Electrophoresis Electrophoresis, Agar Gel Electrophoresis, Polyacrylamide Gel Enzymes Genetic variance Genomes Genotype HLA-DR Antigens - chemistry HLA-DR Antigens - genetics Humans Life Sciences Medicine Microarrays Molecular Sequence Data Mutation Nucleotide sequence Organic Chemistry Physiological aspects Point Mutation Polymerase chain reaction Polymerase Chain Reaction - methods Polymorphism Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide protocol Single nucleotide polymorphisms
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