Association between serum uric acid levels and coronary flow reserve in hypertensive patients without concomitant risk factors

Association between serum uric acid levels and coronary flow reserve in hypertensive patients without concomitant risk factors

Background. Hyperuricemia is associated with hypertension, vascular disease and cardiovascular (CV) disease. However, the role of serum uric acid (SUA) level as an independent risk factor for CV and renal morbidity in hypertension remains controversial. Accordingly, we aimed to determine whether SUA...

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Veröffentlicht in:Blood pressure 2007, Vol.16 (4), p.254-261
Hauptverfasser: Caliskan, Mustafa, Erdogan, Dogan, Gullu, Hakan, Yildirim, Ibrahim, Ozer, Ismail, Yildirir, Aylin, Muderrisoglu, Haldun
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Cardiovascular Diseases - blood
Cohort Studies
Coronary Circulation
Coronary flow reserve
Coronary Vessels - pathology
echocardiography
Echocardiography, Doppler, Color
Female
Humans
hypertension
Hypertension - complications
Hyperuricemia - complications
Male
Middle Aged
ROC Curve
target-organ damage
uric acid
Uric Acid - blood
Ventricular Function
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Zusammenfassung:Background. Hyperuricemia is associated with hypertension, vascular disease and cardiovascular (CV) disease. However, the role of serum uric acid (SUA) level as an independent risk factor for CV and renal morbidity in hypertension remains controversial. Accordingly, we aimed to determine whether SUA levels are independently and specifically associated with coronary flow reserve (CFR) impairment in hypertensive patients. Methods. We examined 80 never treated and newly diagnosed hypertensive individuals. The hypertensive individuals were divided into two groups based on CFR values. Results. Subjects with altered CFR (
ISSN:0803-7051
1651-1999
DOI:10.1080/08037050701428240