Molecular and Biological Characterization of a Mannan-Binding Lectin from the Holothurian Apostichopus Japonicus

To elucidate the origin and evolution of mannan-binding lectins (MBL), a new C-type lectin (CTL) specific for high-mannose glycans (MBL-AJ) was isolated from the coelomic plasma of the holothurian Apostichopus japonicus. MBL-AJ has oligomeric forms with identical 17-kDa subunits on SDS-PAGE. Among n...

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Veröffentlicht in:	Glycobiology (Oxford) 2007-12, Vol.17 (12), p.1284-1298
Hauptverfasser:	Bulgakov, Aleksandr A, Eliseikina, Marina G, Petrova, Irina Yu, Nazarenko, Evgeny L, Kovalchuk, Svetlana N, Kozhemyako, Valery B, Rasskazov, Valery A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apostichopus japonicus bacterial mannans Base Sequence Binding Sites Carbohydrates - chemistry Cucumaria japonica Dimerization echinoderms immunity Glutaral - chemistry Hemagglutinins - chemistry Humans Lectins - chemistry Ligands mannan-binding lectins Mannans - chemistry Mannose-Binding Lectin - chemistry Models, Biological Molecular Sequence Data Sequence Homology, Amino Acid Stichopus - metabolism
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