Membrane Fusion Induced by Neuronal SNAREs Transits through Hemifusion[boxs]

Synaptic transmission requires the controlled release of neurotransmitter from synaptic vesicles by membrane fusion with the presynaptic plasma membrane. SNAREs are the core constituents of the protein machinery responsible for synaptic membrane fusion. The mechanism by which SNAREs drive membrane f...

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Veröffentlicht in:	The Journal of biological chemistry 2005-08, Vol.280 (34), p.30538-30541
Hauptverfasser:	Lu, Xiaobing, Zhang, Fan, McNew, James A., Shin, Yeon-Kyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Electrophoresis, Polyacrylamide Gel Escherichia coli - metabolism Kinetics Lipid Bilayers - chemistry Lipids - chemistry Liposomes - chemistry Membrane Fusion Microscopy, Electron Microscopy, Fluorescence Neurons - metabolism Plasmids - metabolism Protein Binding Recombinant Proteins - chemistry SNARE Proteins Synaptic Transmission Time Factors Vesicular Transport Proteins - metabolism
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