Activation of Ataxia Telangiectasia-mutated DNA Damage Checkpoint Signal Transduction Elicited by Herpes Simplex Virus Infection

Eukaryotic cells are equipped with machinery to monitor and repair damaged DNA. Herpes simplex virus (HSV) DNA replication occurs at discrete sites in nuclei, the replication compartment, where viral replication proteins cluster and synthesize a large amount of viral DNA. In the present study, HSV i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2005-08, Vol.280 (34), p.30336-30341
Hauptverfasser:	Shirata, Noriko, Kudoh, Ayumi, Daikoku, Tohru, Tatsumi, Yasutoshi, Fujita, Masatoshi, Kiyono, Tohru, Sugaya, Yutaka, Isomura, Hiroki, Ishizaki, Kanji, Tsurumi, Tatsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Anhydride Hydrolases Animals Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins - metabolism Cell Line Checkpoint Kinase 2 Chlorocebus aethiops DNA Damage DNA Repair Enzymes - metabolism DNA, Viral DNA-Binding Proteins - metabolism Electrophoresis, Polyacrylamide Gel Fibroblasts - metabolism Gene Silencing Herpes simplex virus Herpesviridae Infections - metabolism Humans Immunoblotting In Situ Hybridization, Fluorescence Kinetics Microscopy, Fluorescence MRE11 Homologue Protein Nuclear Proteins - metabolism Phosphorylation Protein Binding Protein Serine-Threonine Kinases - metabolism Protein Structure, Tertiary RNA, Small Interfering - metabolism Signal Transduction Simplexvirus - metabolism Time Factors Tumor Suppressor Protein p53 - metabolism Tumor Suppressor Proteins - metabolism Ubiquitin - metabolism Ultraviolet Rays Up-Regulation Vero Cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!