Sensitivity to bee venom antigen phospholipase A2: association with specific HLA class I and class II alleles and haplotypes in beekeepers and allergic patients

Bee venom hypersensitivity is a clinical entity of outstanding importance because bee stings are a leading cause of mortality worldwide. Individuals with immediate-type bee venom hypersensitivity, beekeepers, and healthy controls were examined for HLA-DRB1, DQB1, and DQA1 alleles by sequence-specifi...

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Veröffentlicht in:	Human immunology 2005-07, Vol.66 (7), p.818-825
Hauptverfasser:	Sánchez-Velasco, Pablo, Antón, Encarnación, Muñoz, Daniel, Martínez-Quesada, Jorge, Ruíz de Alegría, Carlos, López-Hoyos, Marcos, García-Martín, Alfredo, Jiménez, Isabel, Alonso, Sofía T, Duque, Soledad, Suárez, Alicia, Jerez, Juan, Leyva-Cobián, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	Bee Venoms - immunology Female Gene Frequency - genetics Gene Frequency - immunology Genotype Haplotypes - immunology Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology HLA-A Antigens - genetics HLA-A Antigens - immunology HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-DQ alpha-Chains HLA-DQ Antigens - genetics HLA-DQ Antigens - immunology HLA-DQ beta-Chains HLA-DR Antigens - genetics HLA-DR Antigens - immunology HLA-DRB1 Chains Humans Hypersensitivity, Immediate - genetics Hypersensitivity, Immediate - immunology Likelihood Functions Male Phenotype Phospholipases A - immunology Phospholipases A2 Spain
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