p16/INK4a gene methylation is a frequent finding in pulmonary MALT lymphomas at diagnosis

p16/INK4a gene alterations have been associated with tumor progression in lymphoid malignancies. However, their significance in mucosa-associated lymphoid tissue (MALT) lymphoma is unclear. We investigated p16 gene methylation and mutation in a large series of untreated cases of pulmonary MALT lymph...

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Veröffentlicht in:	Modern pathology 2005-09, Vol.18 (9), p.1187-1192
Hauptverfasser:	Takino, Hisashi, Okabe, Mitsukuni, Li, Chunmei, Ohshima, Koichi, Yoshino, Tadashi, Nakamura, Shigeo, Ueda, Ryuzo, Eimoto, Tadaaki, Inagaki, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over API2–MALT1 fusion DNA Methylation Female gene methylation Genes, p16 Humans Laboratory Medicine lung Lung Neoplasms - genetics Lymphoma, B-Cell - genetics Lymphoma, B-Cell, Marginal Zone - genetics Lymphoma, Large B-Cell, Diffuse - genetics Male MALT lymphoma Medicine Medicine & Public Health Middle Aged Mutation Oncogene Proteins, Fusion - genetics original-article P16/INK4a gene Pathology Polymorphism, Single-Stranded Conformational Reverse Transcriptase Polymerase Chain Reaction
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