Eugenol Inhibits Calcium Currents in Dental Afferent Neurons

Eugenol is a topical analgesic agent widely used in the dental clinic. To elucidate the molecular mechanism underlying its analgesic action, we investigated the effect of eugenol on high-voltage-activated calcium channel (HVACC) currents in dental primary afferent neurons, and with a heterologous ex...

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Veröffentlicht in:	Journal of dental research 2005-09, Vol.84 (9), p.848-851
Hauptverfasser:	Lee, M.H., Yeon, K.-Y., Park, C.-K., Li, H.-Y., Fang, Z., Kim, M.S., Choi, S.-Y., Lee, S.J., Lee, S., Park, K., Lee, J.-H., Kim, J.S., Oh, S.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Local - pharmacology Animals Calcium Channel Blockers - pharmacology Calcium Channels, N-Type - drug effects Cell Line Dental Pulp - innervation Dentistry Eugenol - pharmacology Humans Membrane Potentials - drug effects Neurons, Afferent - drug effects Nociceptors - physiology Rats Receptors, Drug - physiology Trigeminal Ganglion - drug effects TRPV Cation Channels
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