Epithelial Sodium Channel Exit from the Endoplasmic Reticulum Is Regulated by a Signal within the Carboxyl Cytoplasmic Domain of the α Subunit

Epithelial sodium channels (ENaCs) are assembled in the endoplasmic reticulum (ER) from α, β, and γ subunits, each with two transmembrane domains, a large extracellular loop, and cytoplasmic amino and carboxyl termini. ENaC maturation involves transit through the Golgi complex where Asn-linked glyca...

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Veröffentlicht in:	The Journal of biological chemistry 2007-11, Vol.282 (46), p.33475-33483
Hauptverfasser:	Mueller, Gunhild M., Kashlan, Ossama B., Bruns, James B., Maarouf, Ahmad B., Aridor, Meir, Kleyman, Thomas R., Hughey, Rebecca P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cytoplasm - metabolism Dogs Endoplasmic Reticulum - metabolism Epithelial Sodium Channels - metabolism gamma-Glutamyltransferase - metabolism Glycoside Hydrolases - metabolism Golgi Apparatus - metabolism Mice Models, Biological Mutation Protein Structure, Tertiary Time Factors
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