Comparison of tamsulosin and naftopidil for efficacy and safety in the treatment of benign prostatic hyperplasia: a randomized controlled trial

OBJECTIVES To compare the efficacy and safety of two α1a/α1d adrenoceptor (AR) antagonists with different affinity for the α1AR subtypes, tamsulosin and naftopidil, in the treatment of benign prostatic hyperplasia (BPH). PATIENTS AND METHODS Patients with BPH were randomized to receive either tamsul...

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Veröffentlicht in:	BJU international 2005-09, Vol.96 (4), p.581-586
Hauptverfasser:	Gotoh, Momokazu, Kamihira, Osamu, Kinukawa, Tsuneo, Ono, Yoshinari, Ohshima, Shinichi, Origasa, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - therapeutic use Aged Biological and medical sciences Blood Pressure - drug effects Genital system. Reproduction Humans Male Medical sciences naftopidil Naphthalenes - therapeutic use Nephrology. Urinary tract diseases Pharmacology. Drug treatments Piperazines - therapeutic use Prospective Studies prostatic hyperplasia Prostatic Hyperplasia - drug therapy Prostatic Hyperplasia - physiopathology randomized controlled trial Receptors, Adrenergic, alpha-1 - drug effects Statistics, Nonparametric Sulfonamides - therapeutic use tamsulosin Tumors of the urinary system Urinary tract. Prostate gland Urodynamics - drug effects α‐adrenoceptor antagonists
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